Evidence map›Paper›PMID 38392601›Full record

ReviewJournal of personalized medicine2024

The Challenge of Pneumatosis Intestinalis: A Contemporary Systematic Review.

Gennaro Perrone, Mario Giuffrida, Valentina Donato, Gabriele Luciano Petracca, Giorgio Rossi, Giacomo Franzini, Sara Cecconi, Alfredo Annicchiarico, Elena Bonati, Fausto Catena

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. The Clinical Effect of Endoscopic Mucosal Needle Aspiration Combined with Anhydrous Alcohol in the Treatment of Pneumatosis Cystoides Intestinalis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gennaro PerroneDepartment of Emergency Surgery, Maggiore Hospital, 43126 Parma, Italy.ORCID 0000-0001-6502-9195
Mario GiuffridaDepartment of General Surgery, Maggiore Hospital, 43126 Parma, Italy.ORCID 0000-0001-8335-3941
Valentina DonatoDepartment of General Surgery, Maggiore Hospital, 43126 Parma, Italy.
Gabriele Luciano PetraccaDepartment of Emergency Surgery, Maggiore Hospital, 43126 Parma, Italy.
Giorgio RossiDepartment of Emergency Surgery, Maggiore Hospital, 43126 Parma, Italy.
Giacomo FranziniDepartment of Emergency Surgery, Maggiore Hospital, 43126 Parma, Italy.
Sara CecconiDepartment of General Surgery, Maggiore Hospital, 43126 Parma, Italy.
Alfredo AnnicchiaricoDepartment of General Surgery, AUSL Parma, 43125 Parma, Italy.ORCID 0000-0003-3882-776X
Elena BonatiDepartment of Emergency Surgery, Maggiore Hospital, 43126 Parma, Italy.
Fausto CatenaDepartment of Emergency and Trauma Surgey, Bufalini Trauma Center, 47023 Cesena, Italy.ORCID 0000-0001-5558-9965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePneumatosis intestinalis is a radiological finding with incompletely understood pathogenesis. To date, there are no protocols to guide surgical intervention.

methodsA systematic review of literature, according to PRISMA criteria, was performed. Medline and PubMed were consulted to identify articles reporting on the items "emergency surgery, pneumatosis coli, and pneumatosis intestinalis" from January 2010 up to March 2022. This study has not been registered in relevant databases.

resultsA total of 1673 patients were included. The average age was 67.1 ± 17.6 years. The etiology was unknown in 802 (47.9%) patients. Hemodynamic instability (246/1673-14.7% of the patients) was associated with bowel ischemia, necrosis, or perforation (

conclusionsMany variables should be considered in the approach to patients with pneumatosis intestinalis. The challenge facing the surgeons is in truly identifying those who really would benefit and need surgical intervention. The watch and wait policy as a first step seems reasonable, reserving surgery only for patients who are unstable or with high suspicion of bowel ischemia, necrosis, or perforation.

Indexed as

emergencypneumatosis cystoides intestinalisportal vein gasradiologysurgery

Identifiers

PMID38392601
PMCPMC10890206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.