Evidence map›Paper›PMID 38392076›Full record

Trial reportCurrent oncology (Toronto, Ont.)2024

Randomized Double-Blind Placebo-Controlled Study of Salivary Substitute with Enzymatic System for Xerostomia in Patients Irradiated in Head and Neck Region.

Letícia Pacheco Porangaba, Flávio de Melo Garcia, Ana Paula Alvarenga Antonio Rabelo, Amanda Puche Andrade, Fabio de Abreu Alves, Antonio Cássio Assis Pellizzon, Graziella Chagas Jaguar

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Radiation-induced Xerostomia: Evaluation withMolecular imaging and radionuclide therapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Letícia Pacheco PorangabaStomatology Department, A.C. Camargo Cancer Center, São Paulo 01509-010, Brazil.
Flávio de Melo GarciaStomatology Department, A.C. Camargo Cancer Center, São Paulo 01509-010, Brazil.
Ana Paula Alvarenga Antonio RabeloPradel Pharmacy, São Paulo 05592-140, Brazil.
Amanda Puche AndradePradel Pharmacy, São Paulo 05592-140, Brazil.
Fabio de Abreu AlvesStomatology Department, A.C. Camargo Cancer Center, São Paulo 01509-010, Brazil.ORCID 0000-0003-3372-1536
Antonio Cássio Assis PellizzonRadiotherapy Department, A.C. Camargo Cancer Center, São Paulo 01509-010, Brazil.ORCID 0000-0002-2083-5545
Graziella Chagas JaguarStomatology Department, A.C. Camargo Cancer Center, São Paulo 01509-010, Brazil.
AC Camargo Hospital · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to compare whether the use of a salivary substitute including an enzymatic system clinically reduces the intensity of xerostomia, as well as exploring the impact that this has on the quality of life, in patients who had received radiotherapy in the head and neck (HNC) region. Forty patients who had completed radiotherapy treatment within 6 months to 1 year previously were allocated into an Enzymatic Spray group (

Indexed as

Head and Neck NeoplasmsXerostomiaHumansQuality of LifeSalivaSurveys and Questionnaireshead and neck cancerhyposalivationparotid glandradiation injuriesradiotherapysalivary substitutexerostomia

Identifiers

PMID38392076
PMCPMC10887544
OpenAlexW4391994927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.