Evidence map›Paper›PMID 38391935›Full record

ArticleCells2024

The BK Channel Limits the Pro-Inflammatory Activity of Macrophages.

Yihe Chen, Nikita Markov, Lea Gigon, Aref Hosseini, Shida Yousefi, Darko Stojkov, Hans-Uwe Simon

Open access · goldAbstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. The Regulatory Mechanisms of Treponema pallidum Enolase on Macrophages: From Enzymatic Activity to Signal Transduction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Yihe ChenInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.
Nikita MarkovInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.
Lea GigonInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-1142-7283
Aref HosseiniInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.
Shida YousefiInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.
Darko StojkovInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-9243-3759
Hans-Uwe SimonInstitute of Pharmacology, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-9404-7736
University of Bern · CH

Funding

Swiss National Science Foundation 310030_184816
6 · The paper itself

Abstract

Macrophages play a crucial role in the innate immune response, serving as key effector cells in the defense against pathogens. Although the role of the large-conductance voltage and calcium-activated potassium channel, also known as the K

Indexed as

InflammasomesLarge-Conductance Calcium-Activated Potassium ChannelsCalciumCalcium-Calmodulin-Dependent Protein KinasesImmunity, InnateMacrophagesCalciumCalcium-Calmodulin-Dependent Protein KinasesInflammasomesLarge-Conductance Calcium-Activated Potassium ChannelsAIM2 inflammasomeBK channelcalcium influxkinasemacrophage polarizationpro-inflammatory cytokine

Identifiers

PMID38391935
PMCPMC10886595
OpenAlexW4391693737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.