Evidence map›Paper›PMID 38391914›Full record

ArticleCells2024

Molecular Characterization and Subtyping of Breast Cancer Cell Lines Provide Novel Insights into Cancer Relevant Genes.

Claudia Pommerenke, Stefan Nagel, Josephine Haake, Anne Leena Koelz, Matthias Christgen, Laura Steenpass, Sonja Eberth

Open access · goldAbstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Nano-Ayurvedic Medicine Approaches UsingNanotechnology, science and applications · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Claudia PommerenkeDepartment of Bioinformatics, IT and Databases, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.ORCID 0000-0002-9448-416X
Stefan NagelDepartment of Human and Animal Cell Lines, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.ORCID 0000-0003-4431-8988
Josephine HaakeDepartment of Human and Animal Cell Lines, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.
Anne Leena KoelzDepartment of Human and Animal Cell Lines, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.
Matthias ChristgenInstitute of Pathology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-0891-7839
Laura SteenpassDepartment of Human and Animal Cell Lines, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.ORCID 0000-0003-4780-0139
Sonja EberthDepartment of Human and Animal Cell Lines, Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.ORCID 0000-0002-5796-2089
Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures · DEMedizinische Hochschule Hannover · DE

Funding

Deutsche Forschungsgemeinschaft STE1987/11-1
6 · The paper itself

Abstract

Continuous cell lines are important and commonly used in vitro models in breast cancer (BC) research. Selection of the appropriate model cell line is crucial and requires consideration of their molecular characteristics. To characterize BC cell line models in depth, we profiled a panel of 29 authenticated and publicly available BC cell lines by mRNA-sequencing, mutation analysis, and immunoblotting. Gene expression profiles separated BC cell lines in two major clusters that represent basal-like (mainly triple-negative BC) and luminal BC subtypes, respectively. HER2-positive cell lines were located within the luminal cluster. Mutation calling highlighted the frequent aberration of

Indexed as

Breast NeoplasmsCarcinoma, HepatocellularLiver NeoplasmsBreastCarrier ProteinsCell Line, TumorFemaleHumansMitochondrial ProteinsCarrier ProteinsMitochondrial ProteinsRTN4IP1 protein, humanAIM1FGFR2-CRYBG1homeoboxmammary carcinomamiR-99aPAM50RTN4IP1-CRYBG1

Identifiers

PMID38391914
PMCPMC10886524
OpenAlexW4391566495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.