Evidence map›Paper›PMID 38391889›Full record

ArticleJournal of functional biomaterials2024

Design of Laser Activated Antimicrobial Porous Tricalcium Phosphate-Hydroxyapatite Scaffolds for Orthopedic Applications.

Emil Filipov, Ridvan Yildiz, Anna Dikovska, Lamborghini Sotelo, Tharun Soma, Georgi Avdeev, Penka Terziyska, Silke Christiansen, Anne Leriche, Maria Helena Fernandes and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Emil FilipovInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tsarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.ORCID 0000-0002-8373-6034
Ridvan YildizCERAMATHS-Laboratoire de Matériaux Céramiques et de Mathématiques, Département Matériaux et Procédés, University Polytechnique Hauts-de-France, F-59313 Valenciennes, France.
Anna DikovskaInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tsarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.
Lamborghini SoteloInstitute for Nanotechnology and Correlative Microscopy eV INAM, Äußere Nürnberger Str. 62, 91301 Forchheim, Germany.
Tharun SomaInstitute for Nanotechnology and Correlative Microscopy eV INAM, Äußere Nürnberger Str. 62, 91301 Forchheim, Germany.
Georgi AvdeevInstitute of Physical Chemistry, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str. Bld. 11, 1113 Sofia, Bulgaria.
Penka TerziyskaG. Nadjakov Institute of Solid State Physics, Bulgarian Academy of Sciences, Tsarigradsko Chausse 72 Blvd, 1784 Sofia, Bulgaria.
Silke ChristiansenInstitute for Nanotechnology and Correlative Microscopy eV INAM, Äußere Nürnberger Str. 62, 91301 Forchheim, Germany.
Anne LericheCERAMATHS-Laboratoire de Matériaux Céramiques et de Mathématiques, Département Matériaux et Procédés, University Polytechnique Hauts-de-France, F-59313 Valenciennes, France.
Maria Helena FernandesFaculdade de Medicina Dentária, Universidade do Porto, Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal.ORCID 0000-0001-9391-9574
Albena DaskalovaInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tsarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.ORCID 0000-0003-1131-6900
Bulgarian Academy of Sciences · BGUniversité Polytechnique Hauts-de-France · FRFraunhofer Institute for Ceramic Technologies and Systems · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversidade do Porto · PT

Funding

BULGARIAN NATIONAL SCIENCE FUND KP-06-H48/6 (2020-2024)EUROPEAN UNION'S H2020 research and innovation program 861138
6 · The paper itself

Abstract

The field of bone tissue engineering is steadily being improved by novel experimental approaches. Nevertheless, microbial adhesion after scaffold implantation remains a limitation that could lead to the impairment of the regeneration process, or scaffold rejection. The present study introduces a methodology that employs laser-based strategies for the development of antimicrobial interfaces on tricalcium phosphate-hydroxyapatite (TCP-HA) scaffolds. The outer surfaces of the ceramic scaffolds with inner porosity were structured using a femtosecond laser (λ = 800 nm; τ = 70 fs) for developing micropatterns and altering local surface roughness. The pulsed laser deposition of ZnO was used for the subsequent functionalization of both laser-structured and unmodified surfaces. The impact of the fs irradiation was investigated by Raman spectroscopy and X-ray diffraction. The effects of the ZnO-layered ceramic surfaces on initial bacterial adherence were assessed by culturing

Indexed as

antimicrobialbone tissue engineeringfemtosecond laser processingpulsed laser deposition

Identifiers

PMID38391889
PMCPMC10889241
OpenAlexW4391344864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.