Evidence map›Paper›PMID 38391882›Full record

ArticleJournal of functional biomaterials2024

Surface-Mediated Modulation of Different Biological Responses on Anatase-Coated Titanium.

Leila Mohammadnejad, Antonia Theurer, Julia Alber, Barbara Illing, Evi Kimmerle-Mueller, Jacob Schultheiss, Stefanie Krajewski, Frank Rupp

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leila MohammadnejadDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Antonia TheurerDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Julia AlberDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Barbara IllingDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Evi Kimmerle-MuellerDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Jacob SchultheissDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Stefanie KrajewskiDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.
Frank RuppDepartment Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen, Osianderstr. 2-8, 72076 Tübingen, Germany.

Funding

medentis medical, Bad-Neuenahr-Ahrweiler, Germany na
6 · The paper itself

Abstract

Various surface modification strategies are being developed to endow dental titanium implant surfaces with micro- and nano-structures to improve their biocompatibility, and first of all their osseointegration. These modifications have the potential to address clinical concerns by stimulating different biological processes. This study aims to evaluate the biological responses of ananatase-modified blasted/etched titanium (SLA-anatase) surfaces compared to blasted/acid etched (SLA) and machined titanium surfaces. Using unipolar pulsed direct current (DC) sputtering, a nanocrystalline anatase layer was fabricated. In vitro experiments have shown that SLA-anatase discs can effectively promote osteoblast adhesion and proliferation, which are regarded as important features of a successful dental implant with bone contact. Furthermore, anatase surface modification has been shown to partially enhance osteoblast mineralization in vitro, while not significantly affecting bacterial colonization. Consequently, the recently created anatase coating holds significant potential as a promising candidate for future advancements in dental implant surface modification for improving the initial stages of osseointegration.

Indexed as

anatasedental implantfibroblastosseointegration

Identifiers

PMID38391882
PMCPMC10889146

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.