Evidence map›Paper›PMID 38391716›Full record

ArticleBrain sciences2024

Surgical Treatment of Paediatric Thalamic Gliomas-Single-Centre Experience.

David Krahulik, Filip Blazek, Matej Halaj, Lumir Hrabalek, Eva Stepanova, Zdenek Pavelka, Marie Rohanova

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David KrahulikDepartment of Neurosurgery, University Hospital Olomouc, 77900 Olomouc, Czech Republic.ORCID 0000-0002-4907-7960
Filip BlazekDepartment of Neurosurgery, University Hospital Olomouc, 77900 Olomouc, Czech Republic.ORCID 0000-0002-1116-8621
Matej HalajDepartment of Neurosurgery, University Hospital Olomouc, 77900 Olomouc, Czech Republic.ORCID 0000-0002-1877-2194
Lumir HrabalekDepartment of Neurosurgery, University Hospital Olomouc, 77900 Olomouc, Czech Republic.
Eva StepanovaDepartment of Paediatric Neurology, University Hospital Ostrava, 70852 Ostrava, Czech Republic.
Zdenek PavelkaDepartment of Paediatric Oncology, University Hospital Brno, 66263 Brno, Czech Republic.
Marie RohanovaDepartment of Paediatrics, University Hospital Olomouc, 77900 Olomouc, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surgical treatment of paediatric thalamic gliomas has been burdened with high morbidity, and these lesions were often considered inoperable. With new approaches and intraoperative technologies, we can remove tumours once deemed inoperable. In our single centre, we have operated on 11 paediatric patients over the course of 8 years. We have performed eight GTR resections and three intended subtotal resections. The postoperative neurological deficit ranged from mild to very severe for motor weakness and none to severe for aphasia after surgery, with all of the patients improving at 3-month follow-up. Radicality in the surgical approach to thalamic gliomas in children has shown significant benefits when compared to more conservative approaches. For children with LGGs, extensive surgical resection is associated with improved prognosis and longer progression-free survival. However, it does not yield the same proportional benefit for HGGs due to its aggressive nature and worse outlook.

Indexed as

bithalamic gliomaspaediatric thalamic gliomasradical surgery of gliomas in children

Identifiers

PMID38391716
PMCPMC10886717

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.