Evidence map›Paper›PMID 38391563›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Repurposing Mitomycin C in Combination with Pentamidine or Gentamicin to Treat Infections with Multi-Drug-Resistant (MDR)

Elin Svedholm, Benjamin Bruce, Benjamin J Parcell, Peter J Coote

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Surviving Colonies ofAntibiotics (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Busulfan inhibitsFrontiers in cellular and infection microbiology · 2025
    Article
  8. Combined Antibiotic and Photodynamic Therapies inAntibiotics (Basel, Switzerland) · 2024
    Article
  9. Antibiotics (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elin SvedholmBiomedical Sciences Research Complex, School of Biology, University of St Andrews, The North Haugh, St Andrews, Fife KY16 9ST, UK.ORCID 0000-0002-2146-386X
Benjamin BruceBiomedical Sciences Research Complex, School of Biology, University of St Andrews, The North Haugh, St Andrews, Fife KY16 9ST, UK.
Benjamin J ParcellNHS Tayside, Medical Microbiology, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
Peter J CooteBiomedical Sciences Research Complex, School of Biology, University of St Andrews, The North Haugh, St Andrews, Fife KY16 9ST, UK.ORCID 0000-0001-5190-805X
University of St Andrews · GBNHS Tayside · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aims of this study were (i) to determine if the combination of mitomycin C with pentamidine or existing antibiotics resulted in enhanced efficacy versus infections with MDR

Indexed as

antibacterialantibiotic resistanceantibiotic resistance breakercombination therapydrug repurposingGalleria mellonellaMexAB-OprMsynergy

Identifiers

PMID38391563
PMCPMC10886254
OpenAlexW4391752734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.