Evidence map›Paper›PMID 38391529›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Constitutive Activation of RpoH and the Addition of L-arabinose Influence Antibiotic Sensitivity of PHL628

Jenna K Frizzell, Ryan L Taylor, Lisa M Ryno

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. L-Arabinose Alters theMicroorganisms · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jenna K FrizzellDepartment of Chemistry and Biochemistry, Oberlin College, Oberlin, OH 44074, USA.
Ryan L TaylorDepartment of Chemistry and Biochemistry, Oberlin College, Oberlin, OH 44074, USA.
Lisa M RynoDepartment of Chemistry and Biochemistry, Oberlin College, Oberlin, OH 44074, USA.ORCID 0000-0002-9211-8297
Oberlin College · US

Funding

National Science Foundation MCB-2226953Oberlin College Startup FundingResearch Corporation for Science Advancement Cottrell Scholar Award
6 · The paper itself

Abstract

Antibiotics are used to combat the ever-present threat of infectious diseases, but bacteria are continually evolving an assortment of defenses that enable their survival against even the most potent treatments. While the demand for novel antibiotic agents is high, the discovery of a new agent is exceedingly rare. We chose to focus on understanding how different signal transduction pathways in the gram-negative bacterium

Indexed as

antibiotic toleranceheat shock responseL-arabinoseminimum inhibitory concentration (MIC)PHL638 E. coli

Identifiers

PMID38391529
PMCPMC10886279
OpenAlexW4391431753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.