ReviewAntibiotics (Basel, Switzerland)2024
Bloodstream Infection in the Intensive Care Unit: Evolving Epidemiology and Microbiology.
Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for bloodstream infection in COVID-19 patients in intensive care units: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Resistance phenotype, infection source, and empirical therapy in ICU-onset gram-negative bloodstream infections: Associations with 30-day mortality.Irish journal of medical science · 2026Article
- Pathogenic spectrum, antibiotic resistance, and risk factors for 28-day mortality in pediatric bloodstream infection-associated sepsis: a 10-year retrospective cohort study.Microbiology spectrum · 2026Article
- Potential drug-drug interactions and 30-day mortality in ICU patients with bloodstream infection: a single-center retrospective study.BMC infectious diseases · 2026Article
- Prevalence and antimicrobial resistance patterns in patients with blood stream infections: a four-year retrospective study at a tertiary healthcare center in Lebanon.BMC microbiology · 2026Article
- Zone-specific hepatocytes orchestrate the early onset of host immune defenses duringFrontiers in immunology · 2026Article
- Safety and efficacy of early oral switch in Enterobacterales bacteremia: a systematic review and meta-analysis.Journal of Yeungnam medical science · 2026Article
- Bacterial Profile and Antibiotic Resistance of ESKAPEE Pathogens Isolated in Intensive Care Units from Blood Cultures: A Cross-Sectional Study from Abu Dhabi, United Arab Emirates (2018-2022).Antibiotics (Basel, Switzerland) · 2025Article
- Incidence and Risk Factors of Secondary Infections in Critically Ill SARS-CoV-2 Patients: A Retrospective Study in an Intensive Care Unit.Biomedicines · 2025Article
- Anti-Antibiotics (Basel, Switzerland) · 2025Article
- An Evaluation of the ASTar Automated Antimicrobial Testing System for Gram-Negative Bacteria in Positive Blood Cultures.Antibiotics (Basel, Switzerland) · 2025Article
- The Impact of the COVID-19 Pandemic on the Antibiotic Resistance of Gram-Negative Pathogens Causing Bloodstream Infections in an Intensive Care Unit.Biomedicines · 2025Article
- Mortality risk factors in patients with bloodstream infections due to multidrug-resistant Gram-negative bacilli.Frontiers in medicine · 2025Article
- Risk factors associated with mortality and pathogen characteristics of bloodstream infection-induced severe sepsis in the pediatric intensive care unit: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2025Article
- The role of rapid multiplex molecular syndromic panels in the clinical management of infections in critically ill patients: an experts-opinion document.Critical care (London, England) · 2024Review
- Consequences of the COVID-19 Pandemic on the Incidence, Management and Outcomes ofPathogens (Basel, Switzerland) · 2024Article
- Article
- Activity of Aztreonam/Avibactam and Recently Approved β-Lactamase Inhibitor Combinations against Enterobacterales andAntibiotics (Basel, Switzerland) · 2024Article
- Comparing NGS-Based identification of bloodstream infections to traditional culture methods for enhanced ICU care: a comprehensive study.Frontiers in cellular and infection microbiology · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bloodstream infections (BSIs) arising in the intensive care unit (ICUs) present a significant challenge and we completed a narrative review of the emerging literature on this issue. Multiple reports document that these infections are associated with substantial morbidity and mortality. Also, they can be caused by a variety of pathogens. Generally classified as either community or hospital in onset, or as either primary or secondary in origin, the microbiology of ICU BSIs varies across the globe. Gram-positive pathogens predominate in certain regions such as the United States while Gram-negative organisms occur more frequently in Europe, Asia, and Latin America. The incidence of ICU BSIs climbed during the recent pandemic. BSIs complicating the care of persons suffering from Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection significantly heighten the risk for death compared to patients who develop ICU BSIs but who are not infected with SARS-CoV-2. Furthermore, rates of antimicrobial resistance are generally increasing in ICU BSIs. This fact complicates attempts to ensure that the patient receives initially appropriate antimicrobial therapy and is of particular concern in Methicillin-resistant
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