Evidence map›Paper›PMID 38391501›Full record

ArticleAntibiotics (Basel, Switzerland)2024

The Impact of Heterologous Regulatory Genes from Lipodepsipeptide Biosynthetic Gene Clusters on the Production of Teicoplanin and A40926.

Kseniia Zhukrovska, Elisa Binda, Victor Fedorenko, Flavia Marinelli, Oleksandr Yushchuk

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kseniia ZhukrovskaDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.ORCID 0000-0002-1242-5810
Elisa BindaDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-9305-4451
Victor FedorenkoDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.
Flavia MarinelliDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-9195-6777
Oleksandr YushchukDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.ORCID 0000-0003-3296-8297
University of Insubria · ITLviv University · UA

Funding

FEMS Research and Training Grant FEMS-GO-2021-08, 2022FEMS Ukraine Support Grant Application ID - 1787, 2022Fondo Ateneo di Ricerca 2021/2022
6 · The paper itself

Abstract

StrR-like pathway-specific transcriptional regulators (PSRs) function as activators in the biosynthesis of various antibiotics, including glycopeptides (GPAs), aminoglycosides, aminocoumarins, and ramoplanin-like lipodepsipeptides (LDPs). In particular, the roles of StrR-like PSRs have been previously investigated in the biosynthesis of streptomycin, novobiocin, GPAs like balhimycin, teicoplanin, and A40926, as well as LDP enduracidin. In the current study, we focused on StrR-like PSRs from the ramoplanin biosynthetic gene cluster (BGC) in

Indexed as

A40926antibacterial activitychersinamycinpathway-specific regulatory genesproduction improvementramoplaninsoil microorganismsteicoplanin

Identifiers

PMID38391501
PMCPMC10886168
OpenAlexW4391169733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.