Evidence map›Paper›PMID 38391437›Full record

ReviewGels (Basel, Switzerland)2024

NaDES Application in Cosmetic and Pharmaceutical Fields: An Overview.

Carla Villa, Debora Caviglia, Francesco Saverio Robustelli Della Cuna, Guendalina Zuccari, Eleonora Russo

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Green Extraction of Phenolic Compounds from Blueberry (Antioxidants (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Multifunctional NADES-Based Extracts fromMolecules (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Versatility of NADES Across Applications.Molecules (Basel, Switzerland) · 2025
    Review
  14. Article
  15. NaDES-Based Extracts by Microwave Activation fromMolecules (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Natural deep eutectic solvents (NaDES): green solvents for pharmaceutical applications and beyond.Green chemistry : an international journal and green chemistry resource : GC · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carla VillaDepartment of Pharmacy, Section of Drug and Cosmetic Chemistry, Viale Benedetto XV 3, 16132 Genoa, Italy.ORCID 0000-0002-4951-3515
Debora CavigliaDepartment of Pharmacy, Section of Drug and Cosmetic Chemistry, Viale Benedetto XV 3, 16132 Genoa, Italy.
Francesco Saverio Robustelli Della CunaEnvironmental Research Center, ICS Maugeri SPA SB, Institute of Pavia, IRCCS, Via Maugeri 2, 27100 Pavia, Italy.ORCID 0000-0003-3895-7978
Guendalina ZuccariDepartment of Pharmacy, Section of Drug and Cosmetic Chemistry, Viale Benedetto XV 3, 16132 Genoa, Italy.ORCID 0000-0002-9868-6199
Eleonora RussoDepartment of Pharmacy, Section of Drug and Cosmetic Chemistry, Viale Benedetto XV 3, 16132 Genoa, Italy.ORCID 0000-0002-5856-7929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural deep eutectic solvents (NaDES) represent a new generation of green, non-flammable solvents, useful as an efficient alternative to the well-known ionic liquids. They can be easily prepared and exhibit unexpected solubilizing power for lipophilic molecules, although those of a hydrophilic nature are mostly used. For their unique properties, they can be recommend for different cosmetic and pharmaceutical applications, ranging from sustainable extraction, obtaining ready-to-use ingredients, to the development of biocompatible drug delivery responsive systems. In the biomedical field, NaDES can be used as biopolymer modifiers, acting as delivery compounds also known as "therapeutic deep eutectic systems", being able to solubilize and stabilize different chemical and galenical formulations. The aim of this review is to give an overview of the current knowledge regarding natural deep eutectic solvents specifically applied in the cosmetic and pharmaceutical fields. The work could help to disclose new opportunities and challenges for their implementation not only as green alternative solvents but also as potential useful pathways to deliver bioactive ingredients in innovative formulations.

Indexed as

bioactive compound extractionNaDES and cosmeticNaDES and drug deliveryNaDES and formulationsnatural deep eutectic solvents

Identifiers

PMID38391437
PMCPMC10888423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.