ArticleJournal of the American Chemical Society2024
ProPhos: A Ligand for Promoting Nickel-Catalyzed Suzuki-Miyaura Coupling Inspired by Mechanistic Insights into Transmetalation.
Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- DiploPhos: A Hemilabile Bisphosphine for Sterically Hindered Ni-Catalyzed Suzuki-Miyaura Couplings.ACS catalysis · 2026Article
- Access to and unexplored reactivity of nickel-bound 5-membered O- and N-heterocyclic arynesChemical science · 2026Article
- Kinetic Analysis of Transmetalation at Prototypical NickelAngewandte Chemie (International ed. in English) · 2026Article
- Pyridine C─N Transposition via Cycloaddition-Cycloreversion.Angewandte Chemie (International ed. in English) · 2026Article
- Electronic and Steric Effects of the ProPhos Ligand Family for Nickel-Catalyzed Suzuki-Miyaura Coupling of Heteroaromatics.ACS catalysis · 2026Article
- Analyzing the Solvent Effects in Palladium/The journal of physical chemistry. B · 2026Article
- Process-Ready Nickel-Catalyzed Suzuki-Miyaura Coupling Enabled byACS catalysis · 2025Article
- Article
- Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling Reaction of Aliphatic Alcohol Derivatives.Angewandte Chemie (International ed. in English) · 2025Article
- Efficient Nickel Precatalysts for Suzuki-Miyaura Cross-Coupling of Aryl Chlorides and Arylboronic Acids Under Mild Conditions.Angewandte Chemie (International ed. in English) · 2025Article
- "Naked Nickel"-Catalyzed Heteroaryl-Heteroaryl Suzuki-Miyaura Coupling.Angewandte Chemie (International ed. in English) · 2025Article
- Ni-Catalyzed Cyanation of (Hetero)Aryl Electrophiles Using the Nontoxic Cyanating Reagent KACS catalysis · 2025Article
- Ni/PiNe Heterogeneous Catalyst from Biomass Waste: Low-Loading, Ligand-Free Suzuki-Miyaura Cross-Coupling.ChemSusChem · 2025Article
- Deactivation Modes in Nickel-Mediated Suzuki-Miyaura Cross-Coupling Reactions Using an NHC-Pyridonate Ligand.Organometallics · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Nickel-catalyzed Suzuki-Miyaura coupling (Ni-SMC) offers the potential to reduce the cost of pharmaceutical process synthesis. However, its application has been restricted by challenges such as slow reaction rates, high catalyst loading, and a limited scope of heterocycles. Despite recent investigations, the mechanism of transmetalation in Ni-SMC, often viewed as the turnover-limiting step, remains insufficiently understood. We elucidate the "Ni-oxo" transmetalation pathway, applying PPh
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Registered trials
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