Evidence map›Paper›PMID 38390918›Full record

ArticleEpidemiologia (Basel, Switzerland)2024

Genomic Surveillance of SARS-CoV-2: Data Analysis and Assessment of Tunisian Strategy from January 2021 to February 2022.

Arwa Neffati, Mouna Safer, Wissal Kalai, Aicha Hechaichi, Sonia Dhaouadi, Hajer Letaief, Chaima Aichouch, Leila Bouabid, Sondes Darouiche, Nawel El Mili and 5 more

Abstract read
In one paragraph

Article in Epidemiologia (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Long-Term Health Effects of COVID-19 in Tunisia, 2020-2021.International journal of environmental research and public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Arwa NeffatiNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.ORCID 0000-0003-0067-274X
Mouna SaferNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Wissal KalaiNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Aicha HechaichiNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Sonia DhaouadiNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Hajer LetaiefNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Chaima AichouchNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Leila BouabidNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Sondes DarouicheNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Nawel El MiliNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.
Henda TrikiFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis 1006, Tunisia.
Ilhem BoutibaFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis 1006, Tunisia.ORCID 0000-0002-6590-2406
Maha MastouriLaboratory of Microbiology, Fattouma Bourguiba Hospital, Monastir 5000, Tunisia.ORCID 0000-0003-3630-5255
Lamia Fki BerrajahLaboratory of Microbiology, Habib Bourguiba, Sfax 3029, Tunisia.ORCID 0000-0002-4003-0162
Nissaf Bouafif Ben AlayaNational Observatory of New and Emerging Diseases, Tunis 1002, Tunisia.ORCID 0000-0002-3326-9861

Funding

Ministry of helth Tunisia
6 · The paper itself

Abstract

Due to the emergence of the SARS-CoV-2 B.1.1.7 (Alpha) variant in the UK in 2020 and its risk of increased transmission, the Ministry of Health in Tunisia implemented a sequencing surveillance strategy for SARS-CoV-2. The aim of this study was to analyze SARS-CoV-2 genomic surveillance data in Tunisia (January 2021-February 2022) and to assess the implementation of the sequencing strategy for SARS-CoV-2 in accordance with national recommendations and the guidance for SARS-CoV-2 genomic surveillance for public health goals. A descriptive study of all sequenced RT-PCR samples sequenced (January 2021-February2022). An internal audit was also done to assess the compliance against standards covering national recommendations and the Guidance for SARS-CoV-2 genomic surveillance for public health goals. A total of 12 simple or composite requirements related to the following areas were included in the audit standards: sampling (one requirements); data collection/analysis (six requirements); partnership (one requirement); and ethical considerations (one requirement). A total of 4819 samples were sent to laboratories and 4278 samples were sequenced. A total of 3648 samples were classified. Positive variants of concern (VOC) samples were 80.92%, differentiated as follows: Alpha, 40.24%; Beta, 0.24%; Gamma, 0.03%; Delta, 45.26%; and Omicron, 14.19%. Three principal phases of VOCs per ISO-week were shown: Alpha 3/2021-25/2021; Delta 26/2021-2/2022; and Omicron 3/2022-6/2022. Levels of compliance were identified; from a total of 12 requirements, 7 were considered as "not met", 4 as "partially met", and 1 as "fully met" but including not totally achieved objectives. In conclusion, the internal audit of the national SARS-CoV-2 sequencing strategy revealed an overall "not met" level of compliance. The results offered a trigger to collaborate with all stakeholders to develop a surveillance strategy for early detection and response to outbreaks caused by VOCs.

Indexed as

internal auditPublic Health SurveillanceRNASARS-CoV-2SARS-CoV-2 variantssequence analysisTunisia

Identifiers

PMID38390918
PMCPMC10885042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.