Evidence map›Paper›PMID 38390820›Full record

ArticleJournal of the American Heart Association2024

Association Between Pharmacy Proximity With Cardiovascular Medication Use and Risk Factor Control in the United States.

Alexander R Zheutlin, Nasser Sharareh, Jenny S Guadamuz, Ransmond O Berchie, Catherine G Derington, Joshua A Jacobs, Favel L Mondesir, G Caleb Alexander, Emily B Levitan, Monika Safford and 3 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexander R ZheutlinDivision of Cardiology, Feinberg School of Medicine Northwestern University Chicago IL USA.ORCID 0000-0002-5578-782X
Nasser ShararehDepartment of Population Health Sciences, Spencer Fox Eccles School of Medicine University of Utah Salt Lake City UT USA.ORCID 0000-0001-9552-2028
Jenny S GuadamuzDivision of Health Policy and Management University of California, Berkeley, School of Public Health Berkeley CA USA.ORCID 0000-0002-2312-4140
Ransmond O BerchieDepartment of Population Health Sciences, Spencer Fox Eccles School of Medicine University of Utah Salt Lake City UT USA.ORCID 0000-0001-6883-6822
Catherine G DeringtonDepartment of Population Health Sciences, Spencer Fox Eccles School of Medicine University of Utah Salt Lake City UT USA.ORCID 0000-0001-7382-4607
Joshua A JacobsDepartment of Population Health Sciences, Spencer Fox Eccles School of Medicine University of Utah Salt Lake City UT USA.ORCID 0000-0002-9621-9060
Favel L MondesirDepartment of Epidemiology University of Alabama at Birmingham School of Public Health Birmingham AL USA.ORCID 0000-0003-4382-1872
G Caleb AlexanderDepartment of Epidemiology Center for Drug Safety and Effectiveness, Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-5622-2986
Emily B LevitanDepartment of Epidemiology University of Alabama at Birmingham School of Public Health Birmingham AL USA.ORCID 0000-0002-5429-3852
Monika SaffordDivision of General Internal Medicine, Department of Medicine, Weill Cornell Medical College Cornell University New York NY USA.ORCID 0000-0002-3060-0563
Robert O VosSpatial Sciences Institute, Dornsife College of Letters, Arts, and Sciences University of Southern California Los Angeles CA USA.ORCID 0000-0002-7339-7120
Dima M QatoSpatial Sciences Institute, Dornsife College of Letters, Arts, and Sciences University of Southern California Los Angeles CA USA.
Adam P BressDepartment of Population Health Sciences, Spencer Fox Eccles School of Medicine University of Utah Salt Lake City UT USA.ORCID 0000-0002-2259-5039

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)R01HL165452 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2022 to 2025
$8.3M
Utah Stimulating Access to Research in ResidencyR38HL167282 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Margaret B Conroy, JOSEPH BARNEY STANFORD · 2023 to 2026
$924k
NHLBI NIH HHS R38 HL167282NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

backgroundPoor neighborhood-level access to health care, including community pharmacies, contributes to cardiovascular disparities in the United States. The authors quantified the association between pharmacy proximity, antihypertensive and statin use, and blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) among a large, diverse US cohort. METHODS AND

resultsA cross-sectional analysis of Black and White participants in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) study during 2013 to 2016 was conducted. The authors designated pharmacy proximity by census tract using road network analysis with population-weighted centroids within a 10-minute drive time, with 5- and 20-minute sensitivity analyses. Pill bottle review measured medication use, and BP and LDL-C were assessed using standard methods. Poisson regression was used to quantify the association between pharmacy proximity with medication use and BP control, and linear regression for LDL-C. Among 16 150 REGARDS participants between 2013 and 2016, 8319 (51.5%) and 8569 (53.1%) had an indication for antihypertensive and statin medication, respectively, and pharmacy proximity data. The authors did not find a consistent association between living in a census tract with higher pharmacy proximity and antihypertensive medication use, BP control, or statin medication use and LDL-C levels, regardless of whether the area was rural, suburban, or urban. Results were similar among the 5- and 20-minute drive-time analyses.

conclusionsLiving in a low pharmacy proximity census tract may be associated with antihypertensive and statin medication use, or with BP control and LDL-C levels. Although, in this US cohort, outcomes were similar for adults living in high or low pharmacy proximity census tracts.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsPharmaciesPharmacyAdultAntihypertensive AgentsCholesterol, LDLCross-Sectional StudiesHumansRisk FactorsUnited StatesAntihypertensive AgentsCholesterol, LDLHydroxymethylglutaryl-CoA Reductase Inhibitorsantihypertensivedisparitiespharmacy proximityrural–urbanstatin

Identifiers

PMID38390820
PMCPMC10944071

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.