Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
32 authors at 18 institutions in 1 country.
Kensuke MatsushitaUniversité de Strasbourg, Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire, Nouvel Hôpital Civil Centre Hospitalier Universitaire Strasbourg France.ORCID 0000-0002-3722-2921
Clément DelmasIntensive Cardiac Care Unit Rangueil University Hospital/Institute of Metabolic and Cardiovascular Diseases (I2MC), UMR-1048, INSERM Toulouse France.ORCID 0000-0001-9180-9128
Benjamin MarchandotUniversité de Strasbourg, Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire, Nouvel Hôpital Civil Centre Hospitalier Universitaire Strasbourg France.ORCID 0000-0001-7034-1466
François RoubillePhyMedExp, Université de Montpellier, INSERM, CNRS, Cardiology Department CHU de Montpellier Montpellier France.ORCID 0000-0002-5288-9687
Nicolas LamblinUrgences et Soins Intensifs de Cardiologie CHU Lille, University of Lille, Inserm U1167 Lille France.
Meyer ElbazIntensive Cardiac Care Unit Rangueil University Hospital/Institute of Metabolic and Cardiovascular Diseases (I2MC), UMR-1048, INSERM Toulouse France.ORCID 0000-0002-3520-7883
Sebastien ChampionClinique de Parly 2, Ramsay Générale de Santé Le Chesnay France.
Pascal LimUniv Paris Est Créteil, INSERM, IMRB AP-HP, Hôpital Universitaire Henri-Mondor, Service de Cardiologie Créteil France.ORCID 0000-0001-7576-2673
Francis SchneiderMédecine Intensive-Réanimation Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg Strasbourg France.ORCID 0000-0002-7481-5101
Hadi KhachabIntensive Cardiac Care Unit, Department of Cardiology CH d'Aix en Provence Aix-en-Provence France.ORCID 0009-0002-4099-3425
Adrien CarmonaUniversité de Strasbourg, Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire, Nouvel Hôpital Civil Centre Hospitalier Universitaire Strasbourg France.ORCID 0000-0002-3477-208X
Antonin TrimailleUniversité de Strasbourg, Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire, Nouvel Hôpital Civil Centre Hospitalier Universitaire Strasbourg France.ORCID 0000-0001-9279-4220
Jeremy BourenneAix Marseille Université Service de Réanimation des Urgences, CHU La Timone 2 Marseille France.ORCID 0000-0003-3558-8935
Guillaume SchurtzUrgences et Soins Intensifs de Cardiologie CHU Lille, University of Lille, Inserm U1167 Lille France.ORCID 0000-0001-6679-2379
Brahim HarbaouiCardiology Department Hôpital Croix-Rousse and Hôpital Lyon Sud, Hospices Civils de Lyon Lyon France.ORCID 0000-0003-0400-6234
Gerald VanzettoDepartment of Cardiology Hôpital de Grenoble Grenoble France.
Caroline BiendelIntensive Cardiac Care Unit Rangueil University Hospital/Institute of Metabolic and Cardiovascular Diseases (I2MC), UMR-1048, INSERM Toulouse France.
Vincent LabbeService de Médecine Intensive Réanimation, Hôpital Tenon, Département Médico-Universitaire APPROCHES Assistance Publique-Hôpitaux de Paris (APHP), Sorbonne Université Paris France.
Nicolas CombaretDepartment of Cardiology HU Clermont-Ferrand, CNRS, Université Clermont Auvergne Clermont-Ferrand France.ORCID 0000-0003-4905-0765
Jacques MansouratiDepartment of Cardiology University Hospital of Brest and University of Western Brittany Orphy France.ORCID 0000-0002-6697-7194
Emmanuelle FilippiDepartment of Cardiology General Hospital of Atlantic Brittany Vannes France.ORCID 0000-0001-6160-1457
Julien MaizelIntensive Care Department CHU Amiens-Picardie Amiens France.
Benoit LattucaDepartment of Cardiology Nîmes University Hospital, Montpellier University Nîmes France.ORCID 0000-0001-6167-500X
Edouard GerbaudCardiology Intensive Care Unit and Interventional Cardiology Hôpital Cardiologique du Haut Lévêque, Bordeaux Cardio-Thoracic Research Centre, U1045, Bordeaux University, Hôpital Xavier Arnozan Pessac France.ORCID 0000-0003-4669-3562
Eric BonnefoyIntensive Cardiac Care Unit Lyon Brom University Hospital Lyon France.ORCID 0000-0003-3786-9204
Etienne PuymiratCardiology Department European Georges Pompidou Hospital Paris France.ORCID 0000-0002-0533-9682
Laurent BonelloDepartment of Cardiology, Aix-Marseille Université, Intensive Care Unit, Assistance Publique-Hôpitaux de Marseille Hôpital Nord, Mediterranean Association for Research and Studies in Cardiology (MARS Cardio) Marseille France.
Olivier MorelUniversité de Strasbourg, Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire, Nouvel Hôpital Civil Centre Hospitalier Universitaire Strasbourg France.ORCID 0000-0002-7295-3041
Inserm · FRAix-Marseille Université · FRCentre National de la Recherche Scientifique · FRHôpital Civil, Strasbourg · FRCentre hospitalier Bretagne Atlantique · FRCentre Hospitalier du Pays d'Aix · FRCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Grenoble · FRGénérale de Santé · FRHôpital Cardiologique du Haut-Lévêque · FRHôpital Européen Georges-Pompidou · FRHôpitaux Universitaires de Strasbourg · FRSorbonne Université · FRUniversité Claude Bernard Lyon 1 · FRUniversité de Bretagne Occidentale · FRUniversité de Montpellier · FR
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
backgroundThe effects of pharmacological therapy on cardiogenic shock (CS) survivors have not been extensively studied. Thus, this study investigated the association between guideline-directed heart failure (HF) medical therapy (GDMT) and one-year survival rate in patients who are post-CS. METHODS AND
resultsFRENSHOCK (French Observatory on the Management of Cardiogenic Shock in 2016) registry was a prospective multicenter observational survey, conducted in metropolitan French intensive care units and intensive cardiac care units. Of 772 patients, 535 patients were enrolled in the present analysis following the exclusion of 217 in-hospital deaths and 20 patients with missing medical records. Patients with triple GDMT (beta-blockers, renin-angiotensin system inhibitors, and mineralocorticoid receptor antagonists) at discharge (n=112) were likely to have lower left ventricular ejection fraction on admission and at discharge compared with those without triple GDMT (n=423) (22% versus 28%,
conclusionsIn survivors of CS, the one-year mortality rate was significantly lower in those with triple GDMT. Therefore, this study suggests that intensive HF therapy should be considered in patients following CS.
Indexed as
Heart FailureShock, CardiogenicAdrenergic beta-AntagonistsAngiotensin Receptor AntagonistsHumansMulticenter Studies as TopicObservational Studies as TopicProspective StudiesRegistriesStroke VolumeVentricular Function, LeftAdrenergic beta-AntagonistsAngiotensin Receptor Antagonistscardiogenic shockguideline‐directed medical therapyheart failureleft ventricular ejection fractionmortality
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Optimal Heart Failure Medical Therapy and Mortality in Survivors of Cardiogenic Shock: Insights From the FRENSHOCK Registry. · full record | OpenQuestion