Evidence map›Paper›PMID 38390589›Full record

ArticlePhysics and imaging in radiation oncology2024

Automated planning of stereotactic spine re-irradiation using cumulative dose limits.

Sebastian Meyer, Lei Zhang, Yilin Liu, Li Cheng Kuo, Yu-Chi Hu, Yoshiya Yamada, Masoud Zarepisheh, Pengpeng Zhang, Laura Cerviño

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Article
  6. Reirradiation - still navigating uncharted waters?Clinical and translational radiation oncology · 2024
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sebastian MeyerDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Lei ZhangDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Yilin LiuDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Li Cheng KuoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Yu-Chi HuDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Yoshiya YamadaDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Masoud ZarepishehDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Pengpeng ZhangDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Laura CerviñoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background and Purpose: The lack of dedicated tools in commercial planning systems currently restricts efficient review and planning for re-irradiation. The aim of this study was to develop an automated re-irradiation planning framework based on cumulative doses. Materials and Methods: We performed a retrospective study of 14 patients who received spine SBRT re-irradiation near a previously irradiated treatment site. A fully-automated workflow, DART ( Results: All DART plans met institutional physical and cumulative constraints and passed plan checks by qualified medical physicists. DART demonstrated significant improvements in target coverage over clinical plans, with an average increase in PTV D Conclusions: DART provides a powerful framework to achieve more tailored re-irradiation plans by accounting for dose distributions from the previous treatments. The superior plan quality could improve the therapeutic ratio for re-irradiation patients.

Indexed as

Automated planningRe-irradiationSpine SBRT

Identifiers

PMID38390589
PMCPMC10881437

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.