ArticleFrontiers in microbiology2024
Integrated metabolome and microbiome analysis reveals the effect of rumen-protected sulfur-containing amino acids on the meat quality of Tibetan sheep meat.
Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 12 citations in OpenAlex.
- Guanidinoacetic acid enhances Tibetan sheep-meat quality through the gut-muscle axis: insights from metabolome-microbiome integration.Food chemistry. Molecular sciences · 2026Article
- Effects of Rumen-Protected Glycine and Methionine Supplementation in a Low-Protein Diet on Growth and Development, Slaughter Performance, Meat Quality, and Rumen Microflora of Yudong Black Goats.Animals : an open access journal from MDPI · 2026Article
- The effects of castration on the quality of black Tibetan sheep meat and muscle metabolites.Food science of animal resources · 2026Article
- Effects of Perilla Seed Extract Dietary Supplementation on Meat Quality, Rumen Fermentation, and Rumen Microbiome-Metabolome of Tan Lambs.Animals : an open access journal from MDPI · 2026Article
- Research Progress on Muttony Flavor Regulation and the Establishment of Its Digital Intelligent Evaluation System From a Global Perspective.Comprehensive reviews in food science and food safety · 2026Review
- Untargeted metabolomic comparison of breast muscle metabolites between Cobb broilers and local chicken breeds.Poultry science · 2026Article
- Integrated metabolome and microbiome analysis deciphers the effects of resveratrol and β-hydroxy-β-methylbutyric acid on jejunal function under different protein levels in Tibetan sheep.Microbiology spectrum · 2026Article
- Meat Quality Differences Between Ganan Tibetan Sheep and Tianzhu Tibetan Sheep Using Metabolomics and Rumen Microbiota Analyses.Microorganisms · 2026Article
- A pilot study reveals plasma metabolomic and lipidomic signatures of mustard lung disease.Scientific reports · 2026Article
- Effects of Dietary Ammonium Chloride Supplementation on the Lipidome and Volatile Flavor Compounds in the Subcutaneous Adipose Tissue of Tibetan Sheep.Foods (Basel, Switzerland) · 2026Article
- An integrative multi-omics investigation into the influence of forage type on the volatile flavor profile of Ujumqin sheep mutton.Frontiers in veterinary science · 2026Article
- Effects of varying levels of valine supplementation on meat metabolism and rumen microorganisms in Tibetan sheep.Frontiers in microbiology · 2026Article
- Article
- Transport stress alters serum biochemistry and gut microbiota in Tibetan sheep (ovis aries): a 30-day recovery assessment.BMC microbiology · 2025Article
- Effect of Antifreeze Glycopeptides on the Quality and Microstructure of Frozen Lamb Meatballs.Metabolites · 2025Article
- Saline pasture improve meat quality in Qinghai Tibetan sheep through changes in the rumen microbiota.Frontiers in microbiology · 2025Article
- Insights into high-altitude adaptation and meat quality regulation by gastrointestinal metabolites in Tibetan and black pigs.Frontiers in veterinary science · 2025Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study investigated the effects of rumen-protected sulfur-containing amino acids (RPSAA) on the rumen and jejunal microbiota as well as on the metabolites and meat quality of the Methods: By combining 16S rDNA sequencing with UHPLC-Q-TOF MS and Pearson correlation analysis, the relationship between gastrointestinal microbiota, muscle metabolites and meat quality was identified. Results: The results showed that feeding RPSAA can increase the carcass weight, abdominal fat thickness (AP-2 group), and back fat thickness (AP-2 and AP-3 group) of Tibetan sheep. The water holding capacity (WHC), texture, and shear force (SF) of LL in the two groups also increased although the fatty acids content and brightness (L*) value significantly decreased in the AP-2 group. Metabolomics and correlation analysis further showed that RPSAA could significantly influence the metabolites in purine metabolism, thereby affecting L* and SF. In addition, RPSAA was beneficial for the fermentation of the rumen and jejunum. In both groups, the abundance of Discussion: Overall, reducing the levels of crude proteins in the diet and feeding RPSAA is likely to improve the carcass quality of Tibetan sheep, with the addition of RPMET (AP-2) yielding the best edible quality, possibly due to its ability to influence the gastrointestinal microbiota to subsequently regulate muscle metabolites.
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