Evidence map›Paper›PMID 38389059›Full record

SynthesisBMC urology2024

The association between hepatitis B virus and semen quality: a systematic review and meta-analysis.

Yuting Xu, Kai Gan, Liqing Hou, Huawei Wang, June Cai, Liu Liu, Wen Wen, Meng Rao, Li Tang

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yuting Xu *Department of Reproductive genetics, Yan 'an Hospital Affiliated to Kunming Medical University, Kunming, 650051, China.
Kai Gan *Department of Organ Transplantation, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, China.
Liqing HouDepartment of Reproductive genetics, Yan 'an Hospital Affiliated to Kunming Medical University, Kunming, 650051, China.
Huawei WangDepartment of Reproductive genetics, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan Province, 650032, China.
June CaiDepartment of Reproductive genetics, Yan 'an Hospital Affiliated to Kunming Medical University, Kunming, 650051, China.
Liu LiuDepartment of Reproductive genetics, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan Province, 650032, China.
Wen WenDepartment of Reproductive genetics, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan Province, 650032, China.
Meng RaoDepartment of Reproductive genetics, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan Province, 650032, China. rm3816205@163.com.
Li TangDepartment of Reproductive genetics, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan Province, 650032, China. tanglikm@163.com.
Kunming Medical University · CN

Funding

Li Tang National Natural Science Foundation of China (Grant No.82160281)
6 · The paper itself

Abstract

backgroundSome studies have suggested that hepatitis B virus (HBV) infection had a negative association with semen quality, but the conclusions have been inconsistent. The purpose of our study was to systematically assess the association between HBV infection and semen parameters.

methodsWe searched electronic databases for studies published from January 1980 to August 2023. Eleven studies were included in the analysis. Primary outcomes were semen volume, sperm concentration, sperm morphology, sperm motility and sperm progressive motility. We also conducted a subgroup analysis between China and other countries.

resultCompared with the semen quality of HBV-negative men, HBV infection had a negative association with semen volume (MD: -0.20 mL, 95%CI: -0.32 to - 0.09, P = 0.0004), sperm concentration (MD: -4.46 × 10

conclusionHBV infection had a negative association with sperm concentration, motility, morphology, and semen volume. However, The association between HBV and total sperm count remain unclear. This metaanalysis suggests that we should pay attention to the adverse effect of HBV on sperm quality, and several studies have reported the relevant mechanisms. But due to the significant heterogeneity among studies on some semen parameters, further large and well-designed researches are needed before introducing clinical management recommendations.

Indexed as

Hepatitis BSemen AnalysisHepatitis B virusHumansMaleSperm MotilityHepatitis B virusMeta-analysisSemen qualitySystematic review

Identifiers

PMID38389059
PMCPMC10885473
OpenAlexW4392044470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.