ArticleActa neurochirurgica2024
Is two-staged gamma knife surgery a reasonable management option for very large cerebellar metastases? A case series of three patients.
Article in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Upfront frameless hypofractionated gamma knife radiosurgery for large posterior Fossa metastases.Neurosurgical review · 2025Article
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6 authors.
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Abstract
objectiveTwo-staged gamma knife surgery (GKS) is a method that may extend the upper tumor volume limit for using GKS in the management of brain metastases. However, the safety of treating very large posterior fossa lesions with this technique has not been well demonstrated. Therefore, we analyzed our experience in treating cerebellar metastases larger than 12 cm
methodsFour consecutive patients harboring 12 to 30 cm
resultsTumor progression was not demonstrated in any of the patients. Tumor volumes decreased by, on average, more than half between the two stages. The median survival was 22 months, and no patient died due to intracranial tumor progression. Peritumoral edema at the first GKS resolved in all patients, replaced by asymptomatic mild T2 changes in two of them not requiring any treatment. No radiation-induced complication has developed thus far.
conclusionStaged GKS seems to be a feasible management option for very large cerebellar metastases.
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