Evidence map›Paper›PMID 38388868›Full record

ArticleJournal of imaging informatics in medicine2024

An Automated Heart Shunt Recognition Pipeline Using Deep Neural Networks.

Weidong Wang, Hongme Zhang, Yizhen Li, Yi Wang, Qingfeng Zhang, Geqi Ding, Lixue Yin, Jinshan Tang, Bo Peng

Abstract read
In one paragraph

Article in Journal of imaging informatics in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weidong WangSchool of Computer Science and Software Engineering, Southwest Petroleum University, Chengdu, Sichuan, China.
Hongme ZhangDepartment of Cardiovascular Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China. oiczhm@163.com.
Yizhen LiDepartment of Cardiovascular Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Yi WangDepartment of Cardiovascular Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Qingfeng ZhangDepartment of Cardiovascular Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Geqi DingDepartment of Cardiovascular Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Lixue YinDepartment of Cardiovascular Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Jinshan TangDepartment of Health Administration and Policy, College of Public Health, George Mason University, Fairfax, USA.
Bo PengSchool of Computer Science and Software Engineering, Southwest Petroleum University, Chengdu, Sichuan, China. bopeng@swpu.edu.cn.ORCID 0000-0001-8133-3883

Funding

Bureau of Science and Technology Nanchong City SXHZ019Natural Science Foundation of Sichuan Province 2022NSFSC0605Natural Science Foundation of Sichuan Province 2022NSFSC0833Sichuan Provincial Science and Technology Plan 2023YFQ0006
6 · The paper itself

Abstract

Automated recognition of heart shunts using saline contrast transthoracic echocardiography (SC-TTE) has the potential to transform clinical practice, enabling non-experts to assess heart shunt lesions. This study aims to develop a fully automated and scalable analysis pipeline for distinguishing heart shunts, utilizing a deep neural network-based framework. The pipeline consists of three steps: (1) chamber segmentation, (2) ultrasound microbubble localization, and (3) disease classification model establishment. The study's normal control group included 91 patients with intracardiac shunts, 61 patients with extracardiac shunts, and 84 asymptomatic individuals. Participants' SC-TTE images were segmented using the U-Net model to obtain cardiac chambers. The segmentation results were combined with ultrasound microbubble localization to generate multivariate time series data on microbubble counts in each chamber. A classification model was then trained using this data to distinguish between intracardiac and extracardiac shunts. The proposed framework accurately segmented heart chambers (dice coefficient = 0.92 ± 0.1) and localized microbubbles. The disease classification model achieved high accuracy, sensitivity, specificity, F1 score, kappa value, and AUC value for both intracardiac and extracardiac shunts. For intracardiac shunts, accuracy was 0.875 ± 0.008, sensitivity was 0.891 ± 0.002, specificity was 0.865 ± 0.012, F1 score was 0.836 ± 0.011, kappa value was 0.735 ± 0.017, and AUC value was 0.942 ± 0.014. For extracardiac shunts, accuracy was 0.902 ± 0.007, sensitivity was 0.763 ± 0.014, specificity was 0.966 ± 0.008, F1 score was 0.830 ± 0.012, kappa value was 0.762 ± 0.017, and AUC value was 0.916 ± 0.006. The proposed framework utilizing deep neural networks offers a fast, convenient, and accurate method for identifying intracardiac and extracardiac shunts. It aids in shunt recognition and generates valuable quantitative indices, assisting clinicians in diagnosing these conditions.

Indexed as

EchocardiographyNeural Networks, ComputerAdultContrast MediaFemaleHumansImage Interpretation, Computer-AssistedMaleMicrobubblesMiddle AgedContrast MediaDeep learningDisease classificationHeart shuntsSaline contrast transthoracic echocardiography

Identifiers

PMID38388868
PMCPMC11300722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.