Evidence map›Paper›PMID 38388856›Full record

ArticleBritish journal of cancer2024

Age at lung cancer diagnosis in females versus males who never smoke by race and ethnicity.

Batel Blechter, Jason Y Y Wong, Li-Hsin Chien, Kouya Shiraishi, Xiao-Ou Shu, Qiuyin Cai, Wei Zheng, Bu-Tian Ji, Wei Hu, Mohammad L Rahman and 22 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Sex-based inequities in non-small cell lung cancer: gaps and opportunities across the care pathway.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 10 institutions in 3 countries.

Batel Blechter *Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. batel.blechter@nih.gov.ORCID 0000-0001-7610-2554
Jason Y Y Wong *Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Li-Hsin Chien *Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Kouya Shiraishi *Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.ORCID 0000-0002-5821-7400
Xiao-Ou Shu *Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Qiuyin Cai *Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.ORCID 0000-0003-1226-070X
Bu-Tian JiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Wei HuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Mohammad L RahmanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.ORCID 0000-0001-8322-0495
Hsin-Fang JiangInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Fang-Yu TsaiNational Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.
Wen-Yi HuangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.ORCID 0000-0002-4440-3368
Yu-Tang GaoDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Xijing HanVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Mark D SteinwandelVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Gong YangDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Yihe G DaidaCenter for Integrated Health Care Research, Kaiser Permanente Hawai'i, Honolulu, HI, USA.
Su-Ying LiangPalo Alto Medical Foundation Research Institute, Sutter Health, Palo Alto, CA, USA.
Scarlett L GomezGreater Bay Area Cancer Registry, University of California, San Francisco, CA, USA.
Mindy C DeRouenGreater Bay Area Cancer Registry, University of California, San Francisco, CA, USA.
W Ryan DiverDepartment of Population Science, American Cancer Society, Kennesaw, GA, USA.ORCID 0000-0002-5418-9000
Ananya G ReddyDepartment of Population Science, American Cancer Society, Kennesaw, GA, USA.
Alpa V PatelDepartment of Population Science, American Cancer Society, Kennesaw, GA, USA.
Loïc Le MarchandUniversity of Hawaii Cancer Center, Honolulu, HI, USA.
Christopher HaimanGreater Bay Area Cancer Registry, University of California, San Francisco, CA, USA.ORCID 0000-0002-0097-9971
Takashi KohnoDivision of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.
Iona ChengGreater Bay Area Cancer Registry, University of California, San Francisco, CA, USA.
I-Shou ChangNational Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.
Chao Agnes HsiungInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Nathaniel RothmanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Qing LanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
National Cancer Institute · USVanderbilt University Medical Center · USNational Health Research Institutes · TWUniversity of California, San Francisco · USAmerican Cancer Society · USChung Yuan Christian University · TWKaiser Permanente · USShanghai Cancer Institute · CNSutter Health · USUniversity of Hawaiʻi at Mānoa · US

Funding

Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Southern Community Cohort StudyU01CA202979 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., SHRUBSOLE, MARTHA J. · 2016 to 2025
$22.0M
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9M
Shanghai Men's Health StudyUM1CA173640 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHU, XIAO-OU · 2013 to 2017
$4.9M
NCI NIH HHS U01 CA164973NCI NIH HHS U01 CA202979NCI NIH HHS UM1 CA173640NCI NIH HHS UM1 CA182910
6 · The paper itself

Abstract

backgroundWe characterized age at diagnosis and estimated sex differences for lung cancer and its histological subtypes among individuals who never smoke.

methodsWe analyzed the distribution of age at lung cancer diagnosis in 33,793 individuals across 8 cohort studies and two national registries from East Asia, the United States (US) and the United Kingdom (UK). Student's t-tests were used to assess the study population differences (Δ years) in age at diagnosis comparing females and males who never smoke across subgroups defined by race/ethnicity, geographic location, and histological subtypes.

resultsWe found that among Chinese individuals diagnosed with lung cancer who never smoke, females were diagnosed with lung cancer younger than males in the Taiwan Cancer Registry (n = 29,832) (Δ years = -2.2 (95% confidence interval (CI):-2.5, -1.9), in Shanghai (n = 1049) (Δ years = -1.6 (95% CI:-2.9, -0.3), and in Sutter Health and Kaiser Permanente Hawai'i in the US (n = 82) (Δ years = -11.3 (95% CI: -17.7, -4.9). While there was a suggestion of similar patterns in African American and non-Hispanic White individuals. the estimated differences were not consistent across studies and were not statistically significant.

conclusionsWe found evidence of sex differences for age at lung cancer diagnosis among individuals who never smoke.

Indexed as

EthnicityLung NeoplasmsChinaFemaleHumansMaleSmokeUnited StatesWhiteSmoke

Identifiers

PMID38388856
PMCPMC11014844
OpenAlexW4392044341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.