Evidence map›Paper›PMID 38388823›Full record

ArticleForensic toxicology2024

Rapid screening of riot control agents using DART-TD-HRMS.

Lina Mörén, Anders Östin, Andreas Larsson, Julia Forsberg, Daniel Wiktelius, Pernilla Lindén

Abstract read
In one paragraph

Article in Forensic toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lina MörénFOI, Swedish Defence Research Agency, CBRN Defence & Security, SE 901 82, Umeå, Sweden.
Anders ÖstinFOI, Swedish Defence Research Agency, CBRN Defence & Security, SE 901 82, Umeå, Sweden.
Andreas LarssonFOI, Swedish Defence Research Agency, CBRN Defence & Security, SE 901 82, Umeå, Sweden.
Julia ForsbergFOI, Swedish Defence Research Agency, CBRN Defence & Security, SE 901 82, Umeå, Sweden.
Daniel WikteliusFOI, Swedish Defence Research Agency, CBRN Defence & Security, SE 901 82, Umeå, Sweden.
Pernilla LindénFOI, Swedish Defence Research Agency, CBRN Defence & Security, SE 901 82, Umeå, Sweden. pernilla.linden@foi.se.ORCID 0000-0002-8346-1966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRiot Control Agents (RCAs) are chemicals used in law enforcement for non-lethal riot control and use in conflicts between states that violates the Chemical Weapons Convention. OPCW's Scientific Advisory Board has identified sixteen potential RCAs including capsaicinoids, CS, and CR. RCAs may be misused for criminal purposes, so methods for detecting such misuse are needed. This study therefore evaluates the feasibility of a rapid, high throughput screening method of RCAs on surfaces (particularly clothing surfaces) by Direct Analysis in Real Time with a thermal desorption unit coupled to high-resolution mass spectrometry (DART-TD-HRMS).

methodsA broadly applicable method for detecting potential RCAs was developed and tested on cotton fabric samples sprayed with self-defence sprays from an in-house reference stock. The feasibility of detecting RCAs by direct analysis of surface wipe samples placed in the DART source was also investigated.

resultsThe method detected all sixteen RCAs and contaminated clothing were successfully screened for active agents in a reference collection of self-defence sprays. A pilot study also showed that RCAs can be detected by holding a sample directly in front of the DART source.

conclusionDART-TD-HRMS enables rapid and simple screening of RCAs on fabric samples enabling a high sample throughput.

Indexed as

Mass SpectrometryClothingCotton FiberFeasibility StudiesHumansPilot ProjectsTextilesChemical Weapons Convention (CWC)DART-TD-HRMSHigh throughput screeningRiot Control Agent (RCA)Self-defence sprays

Identifiers

PMID38388823
PMCPMC11269514

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.