Evidence map›Paper›PMID 38388636›Full record

ArticleScientific reports2024

Prevalence and impact of fertility concerns in young women with breast cancer.

Samantha Mannion, Alexandra Higgins, Nicole Larson, Elizabeth A Stewart, Zaraq Khan, Chandra Shenoy, Hazel B Nichols, H Irene Su, Ann H Partridge, Charles L Loprinzi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Samantha MannionDepartment of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-9647-0925
Alexandra HigginsDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.ORCID 0000-0001-6626-0700
Nicole LarsonDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.ORCID 0000-0002-2129-6934
Elizabeth A StewartDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-1110-2400
Zaraq KhanDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-5227-0753
Chandra ShenoyDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-2537-3482
Hazel B NicholsDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0003-0972-1560
H Irene SuDepartment of Obstetrics and Gynecology, University of California San Diego, San Diego, CA, USA.ORCID 0000-0002-6671-5151
Ann H PartridgeDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0002-4722-4824
Charles L LoprinziDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.ORCID 0000-0001-8044-5752
Fergus CouchMayo Clinic Comprehensive Cancer Center, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-9417-9985
Janet E OlsonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-4944-7789
Kathryn J RuddyDepartment of Oncology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA. Ruddy.Kathryn@mayo.edu.ORCID 0000-0001-6298-332X
Mayo Clinic in Arizona · USMayo Clinic · USDana-Farber Cancer Institute · USMayo Clinic in Florida · USUniversity of California San Diego · USUniversity of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
Synergizing genome sequencing with advances in patient reprted outcomes (PRO)R01NR015259 · NINR · MAYO CLINIC ROCHESTER · PI RUDDY, KATHRYN JEAN, SLOAN, JEFF A. · 2015 to 2020
$3.2M
NIEHS NIH HHS P30 ES010126NINR NIH HHS R01 NR015259
6 · The paper itself

Abstract

Survey data from the Mayo Clinic Breast Disease Registry were used to assess fertility counseling and fertility preservation strategies in a modern cohort of young women with breast cancer. One hundred respondents were identified who were under age 50 at the time of breast cancer diagnosis and who expressed interest in future childbearing near the time of diagnosis and/or 1 year later. Ninety-three percent of the 81 respondents to the year one survey recalled fertility counseling prior to cancer treatment. Most who reported a high level of fertility concern declared that this concern had impacted their treatment decisions, often shortening their planned duration of endocrine therapy. Approximately half had taken steps to preserve future fertility, and a third had used a gonadotropin-releasing hormone agonist either alone or combined with another method (e.g., embryo or oocyte cryopreservation).

Indexed as

Breast NeoplasmsFertility PreservationCryopreservationFemaleFertilityHumansMiddle AgedPrevalence

Identifiers

PMID38388636
PMCPMC10884010
OpenAlexW4392088440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.