Evidence map›Paper›PMID 38388527›Full record

ArticleNature communications2024

Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.

Zhaoxiang He, Mengchen Wu, Hongtao Tian, Liangdong Wang, Yiqi Hu, Fangzhu Han, Jiancang Zhou, Yong Wang, Long Zhou

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Why Euglenozoans.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  8. Article
  9. Global conformations ofScience advances · 2025
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhaoxiang He *Department of Biophysics and Department of Critical Care Medicine of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Mengchen Wu *Department of Biophysics and Department of Critical Care Medicine of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Hongtao Tian *Department of Biophysics and Department of Critical Care Medicine of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Liangdong WangCollege of Life Sciences, Zhejiang University, Hangzhou, 310058, China.
Yiqi HuDepartment of Biophysics and Department of Critical Care Medicine of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Fangzhu HanDepartment of Biophysics and Department of Critical Care Medicine of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Jiancang ZhouDepartment of Critical Care Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. jiancangzhou@zju.edu.cn.
Yong WangCollege of Life Sciences, Zhejiang University, Hangzhou, 310058, China. yongwang_isb@zju.edu.cn.ORCID 0000-0001-9156-0377
Long ZhouDepartment of Biophysics and Department of Critical Care Medicine of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China. longzhou@zju.edu.cn.ORCID 0000-0002-1864-8951

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32371253National Natural Science Foundation of China (National Science Foundation of China) 32371300
6 · The paper itself

Abstract

Euglena gracilis, a model organism of the eukaryotic supergroup Discoba harbouring also clinically important parasitic species, possesses diverse metabolic strategies and an atypical electron transport chain. While structures of the electron transport chain complexes and supercomplexes of most other eukaryotic clades have been reported, no similar structure is currently available for Discoba, limiting the understandings of its core metabolism and leaving a gap in the evolutionary tree of eukaryotic bioenergetics. Here, we report high-resolution cryo-EM structures of Euglena's respirasome I + III

Indexed as

EuglenaMitochondrial MembranesElectron TransportElectron Transport Complex IVEnergy MetabolismElectron Transport Complex IV

Identifiers

PMID38388527
PMCPMC10884005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.