Evidence map›Paper›PMID 38388496›Full record

ArticleCell death & disease2024

Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence.

Viola Kluge, Melanie Kappelmann-Fenzl, Stefan Fischer, Tom Zimmermann, Michaela Pommer, Silke Kuphal, Anja-Katrin Bosserhoff

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Viola KlugeInstitute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID 0009-0002-2450-6017
Melanie Kappelmann-FenzlInstitute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Stefan FischerFaculty of Computer Science, Deggendorf Institute of Technology, Dieter-Görlitz-Platz 1, 94469, Deggendorf, Germany.
Tom ZimmermannInstitute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Michaela PommerInstitute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Silke KuphalInstitute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Anja-Katrin BosserhoffInstitute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. anja.bosserhoff@fau.de.ORCID 0000-0001-8147-394X
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEDeggendorf Institute of Technology · DE

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) BO1573
6 · The paper itself

Abstract

Oncogene-induced senescence (OIS) is an important process that suppresses tumor development, but the molecular mechanisms of OIS are still under investigation. It is known that BRAF

Indexed as

Melanomabeta CateninCellular SenescenceHumansOncogenesProto-Oncogene Proteins B-rafWnt Signaling Pathwaybeta CateninProto-Oncogene Proteins B-raf

Identifiers

PMID38388496
PMCPMC10883971
OpenAlexW4392041270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.