Evidence map›Paper›PMID 38388360›Full record

ArticleBMC pregnancy and childbirth2024

SARS-CoV-2 infection during pregnancy and the risk of adverse maternal outcomes in the Republic of Georgia: a national birth registry-based cohort study.

Natia Skhvitaridze, Amiran Gamkrelidze, Tinatin Manjavidze, Tormod Brenn, Charlotta Rylander

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Natia SkhvitaridzeDepartment of Community Medicine, UiT The Arctic University of Norway, N-9037, Langnes, Tromsø, PO Box 6050, Norway. natia.skhvitaridze@uit.no.ORCID http://orcid.org/0000-0002-0312-4151
Amiran GamkrelidzeThe University of Georgia, 77a Kostava Street, Tbilisi, Georgia.
Tinatin ManjavidzeDepartment of Community Medicine, UiT The Arctic University of Norway, N-9037, Langnes, Tromsø, PO Box 6050, Norway.ORCID http://orcid.org/0000-0003-1340-6256
Tormod BrennDepartment of Community Medicine, UiT The Arctic University of Norway, N-9037, Langnes, Tromsø, PO Box 6050, Norway.ORCID http://orcid.org/0000-0003-3717-8323
Charlotta RylanderDepartment of Community Medicine, UiT The Arctic University of Norway, N-9037, Langnes, Tromsø, PO Box 6050, Norway.ORCID http://orcid.org/0000-0002-5056-9452
National Center for Disease Control and Public Health · GEUiT The Arctic University of Norway · NOUniversity of Georgia · GE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeorgia experienced an increase in maternal deaths (MD) during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, which warrants further investigation. This study aimed to assess associations between timing of SARS-CoV-2 infection during pregnancy and MD, post-delivery intensive care unit (ICU) admission, and caesarean section (CS) delivery.

methodsWe performed a national birth registry-based cohort study of pregnant women who had completed 22 weeks of gestation and delivered between February 28, 2020, and August 31, 2022. The data were linked to coronavirus disease 2019 (COVID-19) testing, vital, and immunization registries. Pregnant women were classified into three groups: confirmed SARS-CoV-2 infection from conception through 31 days before delivery; confirmed infection within 30 days before or at delivery; and women negative for SARS-CoV-2 infection or without any test results (reference group). Multivariable logistic regression was used to calculate the adjusted odds ratios (aORs) and 95% confidence intervals (CIs).

resultsAmong 111,493 pregnant women, 16,751 had confirmed infection during pregnancy, and 7,332 were fully vaccinated against COVID-19 before delivery. Compared to the reference group, those with confirmed infection within 30 days before or at delivery experienced increased odds of MD (aOR: 43.11, 95% CI, 21.99-84.55), post-delivery ICU admission (aOR: 5.20, 95% CI, 4.05-6.67), and CS delivery (aOR: 1.11, 95% CI, 1.03-1.20).

conclusionsPregnant women in Georgia with confirmed SARS-CoV-2 infection within 30 days before or at delivery experienced a considerably higher risk of MD and post-delivery ICU admission and a slightly higher risk for CS delivery. Additionally, the results highlighted that most pregnant women were not vaccinated against COVID-19. These findings should alert stakeholders that adherence to public health preventive measures needs to be improved.

Indexed as

COVID-19Maternal DeathPregnancy Complications, InfectiousPremature BirthCesarean SectionCohort StudiesFemaleGeorgiaGeorgia (Republic)HumansPregnancyPregnancy OutcomeRegistriesSARS-CoV-2Adverse maternal health outcomesCaesarean sectionIntensive care unitMaternal deathRegistry-based cohort studySARS-CoV-2 infection

Identifiers

PMID38388360
PMCPMC10882809
OpenAlexW4392058200

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.