Evidence map›Paper›PMID 38388231›Full record

ReviewTrends in immunology2024

Durable CD4

Erik P Hughes, Amber R Syage, Dean Tantin

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Erik P HughesDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Amber R SyageDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Dean TantinDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. Electronic address: dean.tantin@path.utah.edu.
University of Utah · US

Funding

Training Program in Microbial PathogenesisT32AI055434 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A, PLANELLES, VICENTE · 2004 to 2025
$6.0M
Role of Transcription Coactivator OCA-B in Gene Poising and Immunological MemoryR01AI100873 · NIAID · UNIVERSITY OF UTAH · PI TANTIN, DEAN · 2013 to 2022
$3.8M
Targeting OCA-B in multiple sclerosisR01AI162929 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DEAN TANTIN · 2022 to 2026
$2.0M
Developmental gene poising by Oct transcription factorsR01GM122778 · NIGMS · UNIVERSITY OF UTAH · PI TANTIN, DEAN · 2018 to 2021
$1.2M
The Neuroimmunology Training Program at the University of UtahT32NS115664 · NINDS · UNIVERSITY OF UTAH · PI O'CONNELL, RYAN M, WILCOX, KAREN S · 2020 to 2024
$988k
NIAID NIH HHS R01 AI100873NIAID NIH HHS R01 AI162929NIAID NIH HHS T32 AI055434NIGMS NIH HHS R01 GM122778NINDS NIH HHS T32 NS115664
6 · The paper itself

Abstract

Mammalian stem cells govern development, tissue homeostasis, and regeneration. Following years of study, their functions have been delineated with increasing precision. The past decade has witnessed heightened widespread use of stem cell terminology in association with durable T cell responses to infection, antitumor immunity, and autoimmunity. Interpreting this literature is complicated by the fact that descriptions are diverse and criteria for labeling 'stem-like' T cells are evolving. Working under the hypothesis that conceptual frameworks developed for actual stem cells can be used to better evaluate and organize T cells described to have stem-like features, we outline widely accepted properties of stem cells and compare these to different 'stem-like' CD4

Indexed as

AutoimmunityCD4-Positive T-LymphocytesAnimalsHumansImmunologic MemoryMammalsantitumor immunityautoimmunityCD4(+) T cellsimmune memory

Identifiers

PMID38388231
PMCPMC10947858
OpenAlexW4391996246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.