Evidence map›Paper›PMID 38388203›Full record

ReviewBMJ case reports2024

Resolution of gastric antral vascular ectasia following cessation of imatinib.

James A Maye, Olivia Baker, Nadim Sheikh

Abstract readCase ReportsReview
In one paragraph

Review in BMJ case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James A MayeMedicine, West Suffolk Hospital, Bury Saint Edmunds, UK j.anthonymaye@gmail.com.ORCID http://orcid.org/0000-0001-8116-1444
Olivia BakerMedicine, West Suffolk Hospital, Bury Saint Edmunds, UK.ORCID http://orcid.org/0000-0002-0038-2657
Nadim SheikhGastroenterology, West Suffolk Hospital, Bury Saint Edmunds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A female patient in her 80s presented with chronic iron-deficiency anaemia secondary to gastric antral vascular ectasia (GAVE), despite repeated endoscopic treatment. Her medical history was notable for chronic myeloid leukaemia, for which she took imatinib. Due to a possible association between imatinib and GAVE described in a small number of case reports, cessation of imatinib was trialled. This led to a significant improvement in the patient's anaemia and resolution of GAVE on repeat endoscopy. GAVE is an uncommon cause of gastrointestinal bleeding, the aetiology of which is uncertain. This report describes an approach to the differential diagnosis of chronic iron-deficiency anaemia and an overview of GAVE syndrome. It illustrates the benefit of broadening the differential when the diagnosis is uncertain and the utility of case reports in informing the differential diagnosis.

Indexed as

Anemia, Iron-DeficiencyAntineoplastic AgentsGastric Antral Vascular EctasiaImatinib MesylateLeukemia, Myelogenous, Chronic, BCR-ABL PositiveAged, 80 and overFemaleGastrointestinal HemorrhageHumansAntineoplastic AgentsImatinib MesylateChronic Myeloid LeukaemiaEndoscopyGastrointestinal systemGI bleedingHaematology (drugs and medicines)

Identifiers

PMID38388203
PMCPMC10884209

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.