Evidence map›Paper›PMID 38387968›Full record

ArticleThe European respiratory journal2024

Neutrophil elastase-dependent cleavage of LTA4H alters its aminopeptidase activity in cystic fibrosis.

Xin Xu, Jin-Dong Li, Todd J Green, Landon Wilson, Kristopher Genschmer, Derek Russell, J Edwin Blalock, Amit Gaggar

Open access · greenAbstract readLetter
In one paragraph

Article in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xin XuDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Jin-Dong LiDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Todd J GreenLung Health Center and Program in Pulmonary Biology, University of Alabama at Birmingham, Birmingham, AL, USA.
Landon WilsonLung Health Center and Program in Pulmonary Biology, University of Alabama at Birmingham, Birmingham, AL, USA.
Kristopher GenschmerDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID https://orcid.org/0000-0002-1836-9522
Derek RussellDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
J Edwin BlalockDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Amit GaggarDivision of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA agaggar@uab.edu.ORCID https://orcid.org/0000-0003-1586-5632
University of Alabama at Birmingham · USTarget (United States) · US

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMIT GAGGAR · 2007 to 2026
$23.0M
Pathogenic Exosomes in COPDR35HL166433 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI J Edwin Blalock · 2023 to 2026
$4.1M
A Novel Proteolytic System of Pulmonary InflammationR01HL102371 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GAGGAR, AMIT · 2010 to 2021
$3.3M
Role of heme and PGP matrikines in lung inflammationR01HL153113 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GAGGAR, AMIT, PATEL, RAKESH P. · 2020 to 2023
$2.2M
CSRD VA I01 CX001969NHLBI NIH HHS R01 HL102371NHLBI NIH HHS R01 HL153113NHLBI NIH HHS R35 HL166433NIDDK NIH HHS P30 DK072482
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cystic FibrosisLeukocyte ElastaseAminopeptidasesHumansNeutrophilsProteolysisAminopeptidasesLeukocyte Elastase

Identifiers

PMID38387968
PMCPMC10918316
OpenAlexW4392032078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.