Evidence map›Paper›PMID 38387550›Full record

ArticleJournal of molecular biology2024

Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.

Cristina M Risi, Betty Belknap, Jennifer Atherton, Isabella Leite Coscarella, Howard D White, P Bryant Chase, Jose R Pinto, Vitold E Galkin

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Thin filament interaction and CaJournal of molecular and cellular cardiology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Myosin-actin crossbridge independent sarcomere length induced CaJournal of molecular and cellular cardiology · 2025
    Article
  16. Article
  17. Dual-filament regulation of relaxation in mammalian fast skeletal muscle.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cristina M RisiDepartment of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Betty BelknapDepartment of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Jennifer AthertonDepartment of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Isabella Leite CoscarellaDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL, USA.
Howard D WhiteDepartment of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
P Bryant ChaseDepartment of Biological Science, Florida State University, Tallahassee, FL, USA.
Jose R PintoDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL, USA.
Vitold E GalkinDepartment of Physiological Sciences, Eastern Virginia Medical School, Norfolk, VA 23507, USA. Electronic address: galkinve@evms.edu.
Eastern Virginia Medical School · USFlorida State University · US

Funding

The mechanisms of cardiac thin filament regulation in health and disease.R01HL160966 · NHLBI · OLD DOMINION UNIVERSITY · PI CHASE, P. BRYANT, GALKIN, VITOLD · 2022 to 2025
$2.3M
300 keV Liquid Helium Robotic MicroscopeS10RR025067 · NCRR · UNIVERSITY OF VIRGINIA · PI EGELMAN, EDWARD H. · 2009 to 2009
$2.0M
NCRR NIH HHS S10 RR025067NHLBI NIH HHS R01 HL160966
6 · The paper itself

Abstract

Cardiac muscle contraction occurs due to repetitive interactions between myosin thick and actin thin filaments (TF) regulated by Ca

Indexed as

ActinsTroponinActomyosinCalciumCryoelectron MicroscopyMyosinsTropomyosinActinsActomyosinCalciumMyosinsTropomyosinTroponincryo-EMmuscle regulationmyosin binding protein Cthin filamenttroponin

Identifiers

PMID38387550
PMCPMC11007730
OpenAlexW4391953090

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.