ArticleClinical medicine (London, England)2024
Tertiary centre study highlights low inpatient deintensification and risks associated with adverse outcomes in frail people with diabetes.
Article in Clinical medicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- A Five-Year Study on Treatment Changes in Hypoglycemia-Associated Medications: Towards Personalized Diabetes Management.Journal of personalized medicine · 2026Article
- The influence of fear of hypoglycemia and frailty on self-efficacy in diabetes management among older adults with type 2 diabetes: a cross-sectional study.Frontiers in psychology · 2026Article
- Frailty-Adjusted Inpatient Glycaemic Targets for Preventing Hypoglycaemia: A Quality Improvement Project.Cureus · 2025Article
- Improving the rates of inpatient HbABMJ open quality · 2025Article
- Editorial: Learnings from all walks of medical practice.Clinical medicine (London, England) · 2024Article
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe community deintensification rates in older people with diabetes are low and hospital admission presents an opportunity for medication review. We audited the inpatient assessment and deintensification rate in people with diabetes and frailty. We also identified factors associated with adverse inpatient outcomes.
methodsA retrospective review of electronic charts was conducted in all people with diabetes and clinical frailty score ≥6 who were discharged from the medical unit in 2022. Data on demographics, comorbidities and background glucose-lowering medications were collected.
resultsSix-hundred-and-sixty-five people with diabetes and moderate/severe frailty were included in our analysis. For people with no HbA1c in the last six months preceding admission, only 9.0% had it assessed during inpatient. Deintensification rates were 19.1%. Factors that were associated with adverse inpatient outcomes included inpatient hypoglycaemia, non-White ethnicity, and being overtreated (HbA1c <7.0% [53 mmol/mol] with any glucose-lowering medication).
conclusionThe assessment and deintensification rate in secondary care for people with diabetes and frailty is low. Inpatient hypoglycaemia, non-White ethnicity, and overtreatment are important factors in determining inpatient outcomes highlighting the importance of deintensification and the need for an evidence-based risk stratification tool.
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