ArticleAmerican journal of respiratory cell and molecular biology2024
Tissue-Resident Alveolar Macrophages Reduce Ozone-induced Inflammation via MerTK-mediated Efferocytosis.
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory cell and molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 15 citations in OpenAlex.
- Ozone Exposure Induces Pulmonary Microbiota Dysbiosis and Associated Inflammatory Responses in Mice.Toxics · 2026Article
- A New Mouse Model for Ozone Health Effects Research.Environmental health perspectives · 2026Article
- Acute ozone exposure results in airway epithelial and immune cell disturbances in mice.Inhalation toxicology · 2026Article
- The cell with many faces: lung macrophage plasticity and function in response to environmental and pathogenic insults.Physiological reviews · 2026Review
- The active role of pulmonary immunity in ischaemic stroke.Journal of neuroinflammation · 2026Review
- CD163 protects against pulmonary injury and inflammation induced by acute ObioRxiv : the preprint server for biology · 2026Article
- Repeated air pollution exposure predisposes to adverse outcomes from acute lung injury.Particle and fibre toxicology · 2026Article
- Screening air pollutants-related genes to construct a prognostic risk model for lung adenocarcinoma and analyzing its immune microenvironment.Journal of thoracic disease · 2026Article
- Research on Therapeutic Strategy of Inhalable Cell Membrane-Coated Nanodelivery Complexes Mediating Nrf2 Pathway for Ameliorating Pulmonary Fibrosis.ACS applied materials & interfaces · 2026Article
- Lipid adsorbed on the surface of nanomaterials enhances protein corona formation.Environmental science. Nano · 2026Article
- Single-cell transcriptomics reveal alveolar macrophage-specific responses in single-hit ozone exposure model in mice.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- The ErbB-tyrosine kinase inhibitor, neratinib, has anti-inflammatory effects in multimorbidity by increasing macrophage efferocytosis via the upregulation of MerTK.Journal of inflammation (London, England) · 2026Article
- Immune evasion of multidrug-resistant bacteria: insights from lung innate immune cells and targeted therapies.Frontiers in cellular and infection microbiology · 2026Review
- High-Altitude Hypoxic Preconditioning Attenuates Lipopolysaccharide-Induced Lung Injury and is Associated with Alveolar-Capillary Barrier Maintenance.Journal of inflammation research · 2026Article
- Profibrotic monocyte-derived alveolar macrophages as a biomarker and therapeutic target in systemic sclerosis-associated interstitial lung disease.bioRxiv : the preprint server for biology · 2025Article
- Evaluating the role of alveolar macrophages in tolerance to ozone.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Single-Cell RNA Sequencing Identifies a Unique Macrophage Population in a Mouse Model of Ozone-induced Asthma Exacerbation.American journal of respiratory cell and molecular biology · 2025Article
- Heterogeneity of Lung Phagocytes and Clearance of Apoptotic Cells in Lung Injury and Repair.Seminars in respiratory and critical care medicine · 2025Review
- Hyaluronan Directs Alveolar Type II Cell Response to Acute Ozone Exposure in Mice.American journal of respiratory cell and molecular biology · 2025Article
- TNF-α-mediated downregulation of CD36 and phagocytic impairment of alveolar macrophages via upregulation of ADAM17 in asthma.Frontiers in immunology · 2025Article
Corrections and comments
- Commented on by
- Update of
Authors and funding
18 authors at 5 institutions in 1 country.
Marissa A GuttenbergDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0003-1737-8002
Aaron T VoseDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0003-2745-7070
Anastasiya BirukovaDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0001-9168-138X
Kaitlyn LewarsDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.
R Ian CummingDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0002-4218-6507
Michaela C AlbrightDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Jasper I MarkDepartment of Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-6499-2198
Claudia J SalazarDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Suchitra SwaminathanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-8292-122X
Zhan YuDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0003-4389-0384
Yuliana V SokolenkoDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0001-9872-0484
Elsie BunyanDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, Illinois.ORCID 0009-0005-6589-6965
Michael J YaegerDivision of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University, Columbus, Ohio; and.ORCID 0000-0001-7039-6360
Michael B FesslerImmunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.ORCID 0000-0002-8262-8613
Loretta G QueDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0001-9188-9244
Kymberly M GowdyDivision of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University, Columbus, Ohio; and.ORCID 0000-0002-7227-0697
Alexander V MisharinDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0003-2879-3789
Robert M TigheDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0002-3465-9861
Duke University · USNorthwestern University · USThe Ohio State University · USNational Institutes of Health · USUniversity of North Carolina at Chapel Hill · US
Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Devalingam Mahalingam · 1993 to 2026
$153.9MCell Signaling of Host DefenseZIAES102005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FESSLER, MICHAEL B · 2009 to 2025
$41.7MTissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAVDEEP S CHANDEL · 2015 to 2026
$26.9MTechnology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7MThe Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9MDuke University Program in Environmental HealthT32ES021432 · NIEHS · DUKE UNIVERSITY · PI Akhenaton-Andrew Dhafir Jones, Joel Newman Meyer · 2013 to 2026
$4.0MCell Signaling of Host DefenseZ01ES102005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FESSLER, MICHAEL B · 2006 to 2008
$3.3MCXCL10/CXCR3 regulation of ozone-induced epithelial permeabilityR01ES027574 · NIEHS · DUKE UNIVERSITY · PI TIGHE, ROBERT MATTHEW · 2018 to 2022
$3.1MMonocyte-derived alveolar macrophage drives inflammatory response to lung ozone exposureR01ES034350 · NIEHS · DUKE UNIVERSITY · PI Alexander Misharin, Robert Matthew Tighe · 2022 to 2026
$3.0MLung transplant injury drives chronic lung allograft dysfunction via recruitment ofmonocyte-derived alveolar macrophagesR01HL153312 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MISHARIN, ALEXANDER · 2020 to 2023
$2.9MTargeting abnormal alveolar immune activation and failed epithelial repair in COVID-19R01HL158139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BUDINGER, GR SCOTT, MISHARIN, ALEXANDER · 2022 to 2025
$2.9MNovel role for CD163 in ozone induced alterations of pulmonary immunityR01ES028829 · NIEHS · OHIO STATE UNIVERSITY · PI GOWDY, KYMBERLY MAE · 2018 to 2022
$2.7MIntramural NIH HHS Z01 ES102005NCI NIH HHS P30 CA060553NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL153312NHLBI NIH HHS R01 HL158139NIAID NIH HHS U19 AI135964NIA NIH HHS P01 AG049665NIA NIH HHS R21 AG075423NIEHS NIH HHS R01 ES027574NIEHS NIH HHS R01 ES028829NIEHS NIH HHS R01 ES034350NIEHS NIH HHS T32 ES021432NIEHS NIH HHS T32ES021432NIEHS NIH HHS Z01 ES102005NIH HHS P01AG049665NIH HHS P01HL154998NIH HHS R01ES027574NIH HHS R01ES028829NIH HHS R01ES034350NIH HHS R01HL153312NIH HHS R01HL158139NIH HHS R21AG075423NIH HHS S10 OD011996NIH HHS U19AI135964
Abstract
Lung inflammation, caused by acute exposure to ozone (O
Indexed as
c-Mer Tyrosine KinaseMacrophages, AlveolarOzonePhagocytosisProto-Oncogene MasAnimalsApoptosisEfferocytosisHumansInflammationLungMaleMiceMice, Inbred C57BLMice, KnockoutPneumoniac-Mer Tyrosine KinaseMAS1 protein, humanMERTK protein, humanMertk protein, mouseOzoneProto-Oncogene MasefferocytosismacrophagesMerTKozone
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.