Evidence map›Paper›PMID 38386664›Full record

ArticleACS infectious diseases2024

Ubiquitin Ligase Parkin Regulates the Stability of SARS-CoV-2 Main Protease and Suppresses Viral Replication.

Li Zhou, Ruochuan Liu, Heather Pathak, Xiaoyu Wang, Geon H Jeong, Pratima Kumari, Mukesh Kumar, Jun Yin

Open access · hybridAbstract read
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Li ZhouDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.ORCID 0000-0002-2815-9430
Ruochuan LiuDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.
Heather PathakDepartment of Biology and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.
Xiaoyu WangDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.
Geon H JeongDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.
Pratima KumariDepartment of Biology and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.
Mukesh KumarDepartment of Biology and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.ORCID 0000-0003-0970-4875
Jun YinDepartment of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, United States.ORCID 0000-0002-4803-7510
Georgia State University · US

Funding

Orthogonal Ubiquitin Transfer to Profile E3 Substrate Specificity.R01GM104498 · NIGMS · UNIVERSITY OF CHICAGO · PI KIYOKAWA, HIROAKI, YIN, JUN · 2013 to 2021
$3.2M
NIGMS NIH HHS R01 GM104498
6 · The paper itself

Abstract

The highly infectious coronavirus SARS-CoV-2 relies on the viral main protease (M

Indexed as

Coronavirus 3C ProteasesCOVID-19Ubiquitin-Protein LigasesAnimalsMiceProtein KinasesSARS-CoV-2UbiquitinVirus Replication3C-like proteinase, SARS-CoV-2Coronavirus 3C Proteasesparkin proteinProtein KinasesUbiquitinUbiquitin-Protein LigasesE3 ubiquitin ligasemain proteasemitophagyParkinSARS-CoV-2

Identifiers

PMID38386664
PMCPMC10928718
OpenAlexW4392080590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.