Evidence map›Paper›PMID 38386597›Full record

ArticlemBio2024

Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls

Mariano Martinez, Anthony Bouillon, Sébastien Brûlé, Bertrand Raynal, Ahmed Haouz, Pedro M Alzari, Jean-Christophe Barale

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mariano Martinez *Unité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.
Anthony Bouillon *Unité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.
Sébastien BrûléPlate-forme de Biophysique Moleculaire-C2RT, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.
Bertrand RaynalPlate-forme de Biophysique Moleculaire-C2RT, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.
Ahmed HaouzPlate-forme de Cristallographie-C2RT, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.ORCID 0000-0003-1196-1635
Pedro M AlzariUnité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.ORCID 0000-0002-4233-1903
Jean-Christophe BaraleUnité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université Paris Cité, Paris, France.ORCID 0000-0002-1203-0376
Centre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR-11-RPIB-002Agence Nationale de la Recherche ANR-19-CE18-0010
6 · The paper itself

Abstract

Malaria symptoms are associated with the asexual multiplication of

Indexed as

Malaria, FalciparumPlasmodiumAnimalsDimerizationErythrocytesHumansHydrogen-Ion ConcentrationMerozoitesPlasmodium falciparumProtozoan ProteinsSubtilisinProtozoan ProteinsSubtilisin3D structureegressenzyme regulationmalariaPlasmodiumpro-domainsubtilin-like protease

Identifiers

PMID38386597
PMCPMC10936178
OpenAlexW4392030324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.