Evidence map›Paper›PMID 38386340›Full record

ReviewCurrent opinion in cardiology2024

Metabolic basis of cardiac dysfunction in cancer patients.

Jane C Figueiredo, Neil Adri Bhowmick, Anja Karlstaedt

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Therapeutic Insights intoPharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jane C FigueiredoDepartment of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center.
Neil Adri BhowmickDepartment of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center.
Anja KarlstaedtAdvanced Clinical Biosystems Research Institute.
Cedars-Sinai Medical Center · USCedars-Sinai Smidt Heart Institute · US

Funding

The paradoxical roles of beta hydroxy butyrate in the liver pro-metastatic nicheP01CA233452 · NCI · CEDARS-SINAI MEDICAL CENTER · PI BHOWMICK, NEIL A., LU, SHELLY CHI-LOO · 2020 to 2024
$9.5M
Novel Biomarkers for Cancer-Related Fatigue: Integrating Metabolomics, Genomics and BehaviorsR01NR018762 · NINR · CEDARS-SINAI MEDICAL CENTER · PI FIGUEIREDO, JANE C., JIM, HEATHER S.L. · 2020 to 2024
$3.4M
Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral originsR01CA238087 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI FIGUEIREDO, JANE C., SCHMIT, STEPHANIE L. · 2019 to 2024
$3.2M
Metabolic Rewiring of the Heart Through Reductive CarboxylationR00HL141702 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI KARLSTAEDT, ANJA · 2021 to 2023
$747k
NCI NIH HHS P01 CA233452NCI NIH HHS R01 CA238087NHLBI NIH HHS R00 HL141702NINR NIH HHS R01 NR018762
6 · The paper itself

Abstract

purpose of reviewThe relationship between metabolism and cardiovascular diseases is complex and bidirectional. Cardiac cells must adapt metabolic pathways to meet biosynthetic demands and energy requirements to maintain contractile function. During cancer, this homeostasis is challenged by the increased metabolic demands of proliferating cancer cells. RECENT

findingsTumors have a systemic metabolic impact that extends beyond the tumor microenvironment. Lipid metabolism is critical to cancer cell proliferation, metabolic adaptation, and increased cardiovascular risk. Metabolites serve as signals which provide insights for diagnosis and prognosis in cardio-oncology patients. SUMMARY: Metabolic processes demonstrate a complex relationship between cancer cell states and cardiovascular remodeling with potential for therapeutic interventions.

Indexed as

Heart DiseasesNeoplasmsHumansLipid MetabolismMetabolic Networks and PathwaysTumor Microenvironment

Identifiers

PMID38386340
PMCPMC11185275
OpenAlexW4392032867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.