Evidence map›Paper›PMID 38386184›Full record

ArticleMikrochimica acta2024

Molecularly imprinted electrochemiluminescence sensor based on a novel luminol derivative for detection of human serum albumin via click reaction.

Wei Li, Guangyan Liu, Fang He, Shili Hou

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wei LiCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Guangyan LiuCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China. gyliudd@126.com.
Fang HeCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Shili HouCollege of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China. houshili@glut.edu.cn.ORCID http://orcid.org/0000-0003-3753-7461
Guilin University of Technology · CN

Funding

Guangxi science and technology base and talent special project 2018AD19154
6 · The paper itself

Abstract

A novel luminol derivative of N-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-5-yl)acrylamide (DTA) with excellent luminescence efficiency was designed and synthesized. Furthermore, a molecularly imprinted electrochemiluminescence sensor (MIECLS) was fabricated to detect ultratrace levels of human serum albumin (HSA) with high sensitivity and selectivity via a click reaction. The molecularly imprinted polymers (MIPs) were formed on the electrode surface via electropolymerization with HSA as a template molecule and catechol as a monomer. In the detection process, the -SH group of HSA on the electrode and the C = C bond of acryloyl group in DTA formed a new C-S bond via the Michael addition reaction to construct the MIECLS. The higher the concentration of HSA, the greater electrochemiluminescence (ECL) intensity measured. Taking advantage of MIECLS for ECL detection (scanning potential, - 0.4 to 0.5 V), there was a good linear relationship between ECL intensity and the logarithm of HSA concentration in the range 5 × 10

Indexed as

AcrylamideLuminolElectrochemical TechniquesElectrodesHumansSerum Albumin, HumanAcrylamideLuminolSerum Albumin, HumanClick reactionHSALuminol derivativeMIECLSModified electrode

Identifiers

PMID38386184
OpenAlexW4392036091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.