Evidence map›Paper›PMID 38386169›Full record

ReviewClinical and experimental medicine2024

Intestinal microbiota regulates the gut-thyroid axis: the new dawn of improving Hashimoto thyroiditis.

Xiaxin Zhu, Chi Zhang, Shuyan Feng, Ruonan He, Shuo Zhang

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical and experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaxin Zhu *Zhejiang Chinese Medical University, Hangzhou, 310053, People's Republic of China.
Chi Zhang *Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, 310018, People's Republic of China.
Shuyan Feng *Zhejiang Chinese Medical University, Hangzhou, 310053, People's Republic of China.
Ruonan HeZhejiang Chinese Medical University, Hangzhou, 310053, People's Republic of China.
Shuo ZhangThe Second Affiliated Hospital of Zhejiang Chinese Medical University (The Xin Hua Hospital of Zhejiang Province), No. 318 Chaowang Road, Hangzhou, 310005, Zhejiang, People's Republic of China. zhangshuotcm@126.com.
Zhejiang Chinese Medical University · CNSir Run Run Shaw Hospital · CN

Funding

National Natural Science Foundation of China 82074214Research Fund Project of Zhejiang Chinese Medical University 2019ZY02
6 · The paper itself

Abstract

Intestinal microbiota plays an indispensable role in the host's innate immune system, which may be related to the occurrence of many autoimmune diseases. Hashimoto thyroiditis (HT) is one of the most common autoimmune diseases, and there is plenty of evidence indicating that HT may be related to genetics and environmental triggers, but the specific mechanism has not been proven clearly. Significantly, the composition and abundance of intestinal microbiota in patients with HT have an obvious difference. This phenomenon led us to think about whether intestinal microbiota can affect the progress of HT through some mechanisms. By summarizing the potential mechanism of intestinal microflora in regulating Hashimoto thyroiditis, this article explores the possibility of improving HT by regulating intestinal microbiota and summarizes relevant biomarkers as therapeutic targets, which provide new ideas for the clinical diagnosis and treatment of Hashimoto thyroiditis.

Indexed as

Autoimmune DiseasesGastrointestinal MicrobiomeHashimoto DiseaseHumansAutoimmune diseaseBiomarkerGut-thyroid axisHashimoto thyroiditisIntestinal microbiota

Identifiers

PMID38386169
PMCPMC10884059
OpenAlexW4392044405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.