Evidence map›Paper›PMID 38386087›Full record

ArticleInternational orthopaedics2024

Surgical treatment of osteogenesis imperfecta: a summary of the incidence of femoral implant-related complications in children with Sillence type I, III and IV.

Bo Li, Hongjiang Yang, Wenbiao Zhu, Shijie Gao, Cong Xing, Shibo Zhu, Hao Li, Hao Zhong, Yang Xiong, Xiuzhi Ren and 1 more

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Article in International orthopaedics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Bo Li *Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Hongjiang Yang *Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Wenbiao Zhu *Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Shijie GaoDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Cong XingDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Shibo ZhuDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Hao LiDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Hao ZhongDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Yang XiongDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China.
Xiuzhi RenDepartment of Pediatric Orthopedics, Wuqing People Hospital, Tianjin, 301700, China. 1313253391@163.com.
Guangzhi NingDepartment of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China. gzning@tmu.edu.cn.ORCID 0000-0002-1635-9902
Tianjin Medical University General Hospital · CNTianjin University · CNWuqing District People's Hospital · CN

Funding

Basic Research Cooperation Project of Beijing-Tianjin-Hebei 20JCZXJC00080National Natural Science Foundation of China 82072439Outstanding Youth Foundation of Tianjin Medical University General Hospital 22ZYYJQ01Tianjin Health Key Discipline Special Project TJWJ2022XK011
6 · The paper itself

Abstract

purposeThis study explored the incidence of IRCs used in the procedures of the femur in children with osteogenesis imperfecta (OI) and investigated the independent risk factors of IRCs.

methodsThree hundred eight-eight cases of surgical data about children with OI were included, who were treated with plate, elastic nail, Kirschner wire and telescopic rod. The choice of different procedures depended on the age of children, the status of femur and the availability of devices. Patient demographics and major IRCs were recorded to compare the outcomes of the four procedures. Then, Cox proportional hazard regression was used to analyse the independent risk factors of IRC, and subgroup analysis was applied to further verify the above results.

resultsThe total incidence of IRC in the four groups was 90.1% (191/212) for plate, 96.8% (30/31) for Kirschner wire, 87.7% (57/65) for elastic nail and 30.0% (24/80) for telescopic rod. The incidence of IRC in the telescopic rod was lower than that in plate, elastic nail and Kirschner wire (P < 0.001). Cox proportional hazard regression analysis confirmed that procedure was the independent risk factor of IRC (HR, 0.191; 95% CI, 0.126-0.288; P < 0.001), fracture (HR, 0.193; 95% CI, 0.109-0.344; P < 0.001) and deformity (HR, 0.086; 95% CI, 0.027-0.272; P < 0.001). In addition, age of surgery was the independent risk factor of fracture (HR, 0.916; 95% CI, 0.882-0.952; P < 0.001) and deformity (HR, 1.052; 95% CI, 1.008-1.098; P = 0.019). Subgroup analysis confirmed that age of surgery, gender, classification, preoperative state and angle did not affect the effect of telescopic rod on reducing the risk of IRCs.

conclusionsIn our cohort, lower incidence of IRCs was observed in telescopic rod group compared with plate, Kirschner wire and elastic nail. Procedure and age of surgery were independent risk factors of fracture. Likewise, procedure and age of surgery were independent risk factors of deformity, and procedure was independent risk factors of IRC.

Indexed as

Bone NailsFemoral FracturesOsteogenesis ImperfectaAdolescentBone PlatesBone WiresChildChild, PreschoolFemaleFemurHumansIncidenceInfantMalePostoperative ComplicationsProportional Hazards ModelsImplant-related complicationsOrthopaedicsOsteogenesis imperfectaSurgery

Identifiers

PMID38386087
OpenAlexW4392053933

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.