Evidence map›Paper›PMID 38386017›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2024

Toward Generalizable Machine Learning Models in Speech, Language, and Hearing Sciences: Estimating Sample Size and Reducing Overfitting.

Hamzeh Ghasemzadeh, Robert E Hillman, Daryush D Mehta

Abstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Machine learning models for predicting response to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer brain metastases: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  17. Speech Acoustic Markers Can Detect Mild Cognitive Impairment in Parkinson's Disease.IEEE journal of selected topics in signal processing · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hamzeh GhasemzadehCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston.ORCID 0000-0001-5395-1908
Robert E HillmanCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston.ORCID 0000-0002-7374-994X
Daryush D MehtaCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston.ORCID 0000-0002-6535-573X

Funding

Use of ambulatory biofeedback to improve behavioral treatment of vocal hyperfunctionP50DC015446 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI Robert E Hillman · 2017 to 2026
$25.5M
Advanced Research Training in Communication Sciences and DisordersT32DC013017 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Cara E. Stepp · 2016 to 2026
$4.9M
Objective assessment of vocal fatigue in laboratory and real-world settingsK99DC021235 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI GHASEMZADEH, HAMZEH · 2023 to 2024
$266k
NIDCD NIH HHS K99 DC021235NIDCD NIH HHS P50 DC015446NIDCD NIH HHS T32 DC013017
6 · The paper itself

Abstract

purposeMany studies using machine learning (ML) in speech, language, and hearing sciences rely upon cross-validations with single data splitting. This study's first purpose is to provide quantitative evidence that would incentivize researchers to instead use the more robust data splitting method of nested

methodFirst, the significant impact of different cross-validations on ML outcomes was demonstrated using real-world clinical data. Then, Monte Carlo simulations were used to quantify the interactions among the employed cross-validation method, the discriminative power of features, the dimensionality of the feature space, the dimensionality of the model, and the sample size. Four different cross-validation methods (single holdout, 10-fold, train-validation-test, and nested 10-fold) were compared based on the statistical power and confidence of the resulting ML models. Distributions of the null and alternative hypotheses were used to determine the minimum required sample size for obtaining a statistically significant outcome (5% significance) with 80% power. Statistical confidence of the model was defined as the probability of correct features being selected for inclusion in the final model.

resultsML models generated based on the single holdout method had very low statistical power and confidence, leading to overestimation of classification accuracy. Conversely, the nested 10-fold cross-validation method resulted in the highest statistical confidence and power while also providing an unbiased estimate of accuracy. The required sample size using the single holdout method could be 50% higher than what would be needed if nested

conclusionThe adoption of nested SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.25237045.

Indexed as

Machine LearningSpeechHearingHumansLanguageSample Size

Identifiers

PMID38386017
PMCPMC11005022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.