Evidence map›Paper›PMID 38385972›Full record

ArticleBiochemistry2024

Characterization of the Zinc Uptake Repressor (Zur) from

Minyong Kim, My Tra Le, Lixin Fan, Courtney Campbell, Sambuddha Sen, Daiana A Capdevila, Timothy L Stemmler, David P Giedroc

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. New Insights intoPathogens (Basel, Switzerland) · 2026
    Review
  2. Cobalt mitigates zinc-starvation effects in Pseudomonas aeruginosa.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Minyong KimDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405-7102, United States.
My Tra LeDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, United States.
Lixin FanBasic Science Program, Frederick National Laboratory for Cancer Research, SAXS Core Facility of the National Cancer Institute, Frederick, Maryland 21702, United States.
Courtney CampbellDepartment of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48201-2417, United States.
Sambuddha SenDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405-7102, United States.
Daiana A CapdevilaFundación Instituto Leloir, Instituto de Investigaciones Bioquímicas de Buenos Aires (IIBBA-CONICET), C1405 BWE Buenos Aires, Argentina.ORCID 0000-0002-0500-1016
Timothy L StemmlerDepartment of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48201-2417, United States.
David P GiedrocDepartment of Chemistry, Indiana University, Bloomington, Indiana 47405-7102, United States.ORCID 0000-0002-2342-1620
Indiana University Bloomington · USWayne State University · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARFrederick National Laboratory for Cancer Research · US

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
Transition Metal Homeostasis and Reactive Sulfur Species in Bacterial PathogensR35GM118157 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI DAVID P. GIEDROC · 2016 to 2026
$5.9M
NCI NIH HHS 75N91019D00024NIAID NIH HHS R01 AI101171NIGMS NIH HHS R35 GM118157
6 · The paper itself

Abstract

Bacterial cells tightly regulate the intracellular concentrations of essential transition metal ions by deploying a panel of metal-regulated transcriptional repressors and activators that bind to operator-promoter regions upstream of regulated genes. Like other zinc uptake regulator (Zur) proteins,

Indexed as

Acinetobacter baumanniiIsoquinolinesSulfonamidesBacterial ProteinsBinding SitesCadmiumDNAMetalsProtein SubunitsRepressor ProteinsScattering, Small AngleX-Ray DiffractionZincBacterial ProteinsCadmiumDNAIsoquinolinesMetalsN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideProtein SubunitsRepressor ProteinsSulfonamidesZinc

Identifiers

PMID38385972
PMCPMC11019503
OpenAlexW4392038460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.