Evidence map›Paper›PMID 38385646›Full record

ArticleMicrobiology spectrum2024

Analysis on the change of gut microbiota and metabolome in lung transplant patients.

Zhichao Hou, Tangjuan Zhang, Zheng Ding, Ting Qian, Peng Wang, Bo Wu, Xue Pan, Xiangnan Li

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhichao HouDepartment of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Tangjuan ZhangDepartment of Emergency, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zheng DingDepartment of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ting QianTransplant Center, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Peng WangSchool of Nursing and Health, Zhengzhou University, Zhengzhou, China.
Bo WuTransplant Center, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Xue PanSchool of Nursing and Health, Zhengzhou University, Zhengzhou, China.
Xiangnan LiDepartment of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0009-0006-8144-2725
First Affiliated Hospital of Zhengzhou University · CNWuxi People's Hospital · CNZhengzhou University · CN

Funding

Engineering Laboratory of Henan Province 20211013Henan Province medical science and technology research plan joint construction projects LHGJ20190027 and LHGJ20190109Joint construction by provinces and the Ministry of Education SBGJ202002015 Wjlx2020080MOST | National Natural Science Foundation of China (NSFC) 32070623The advanced medical research center of Zhengzhou University XKZDQY202006
6 · The paper itself

Abstract

Previous studies have shown that the gut microbiota and its metabolites are associated with the success of organ transplantation. However, the specific changes in the gut microbiota of lung transplant patients remain unclear. Hence, this study aimed to elucidate the interplay between the gut microbiota, metabolome, and lung transplantation outcomes. Using 16S metagenomics sequencing and untargeted metabolic profiling, we conducted a comprehensive analysis of gut microbial and metabolic alterations in lung transplant recipients relative to non-transplant group. Our findings revealed the predominance of IMPORTANCE: This study has profound implications for lung transplantation as it uncovers the important role of gut microbiota and metabolome in shaping transplantation outcomes. The identification of dominant bacterial genera, such as

Indexed as

Gastrointestinal MicrobiomeLung TransplantationEnterococcusHumansImmunoglobulin AMetabolomeRNA, Ribosomal, 16STretinoinImmunoglobulin ARNA, Ribosomal, 16STretinoingut microbiotalung transplantationmetabolometransplant rejection

Identifiers

PMID38385646
PMCPMC10986604
OpenAlexW4392082770

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.