Evidence map›Paper›PMID 38385627›Full record

ArticleCancer biology & therapy2024

SATB1 mediated tumor colonization and β-catenin nuclear localization are associated with colorectal cancer progression.

Luan Sun, Feng Wang, Xufei Wang, Feiying Zhang, Sujuan Ma, Jinghuan Lv

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luan SunDepartment of Cell Biology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, P.R. China.ORCID 0009-0004-7560-4826
Feng WangDepartment of Pathology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, P.R. China.
Xufei WangDepartment of Cell Biology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
Feiying ZhangThe second Clinical Medical School of Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
Sujuan MaDepartment of Cell Biology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, P.R. China.
Jinghuan LvDepartment of Pathology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, P.R. China.ORCID 0000-0003-1746-420X
Nanjing Medical University · CNSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a malignancy with high incidence and poor prognosis. It is urgent to identify valuable biomarkers for early diagnosis and potent therapeutic targets. It has been reported that SATB1 is associated with the malignant progression in CRC. To explore the role of SATB1 in CRC progression and the underlying mechanism, we evaluated the expression of SATB1 in the paired CRC tissues with immunohistochemistry. The results showed that the expression of SATB1 in lymph node metastasis was higher than that in primary lesion, and that in distant organ metastasis was higher than that in primary lesion. The retrospective analysis showed that patients with high expression of SATB1 had a significantly worse prognosis than those with negative and moderate expression.

Indexed as

Colorectal NeoplasmsMatrix Attachment Region Binding Proteinsbeta CateninCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansPrognosisRetrospective StudiesTranscription FactorsWnt Signaling Pathwaybeta CateninMatrix Attachment Region Binding ProteinsSATB1 protein, humanTranscription FactorsColorectal cancer progressionSATB1tumor colonizationβ-catenin

Identifiers

PMID38385627
PMCPMC10885174
OpenAlexW4392045777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.