Evidence map›Paper›PMID 38385182›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024

Assessing the pulmonary vascular responsiveness to oxygen with proton MRI.

Abhilash S Kizhakke Puliyakote, Vincent Tedjasaputra, Gregory M Petersen, Rui Carlos Sá, Susan R Hopkins

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abhilash S Kizhakke PuliyakotePulmonary Imaging Laboratory, UC San Diego Health Sciences, La Jolla, California, United States.ORCID 0000-0003-4541-0786
Vincent TedjasaputraPulmonary Imaging Laboratory, UC San Diego Health Sciences, La Jolla, California, United States.ORCID 0000-0003-3217-0285
Gregory M PetersenPulmonary Imaging Laboratory, UC San Diego Health Sciences, La Jolla, California, United States.
Rui Carlos SáPulmonary Imaging Laboratory, UC San Diego Health Sciences, La Jolla, California, United States.ORCID 0000-0002-8885-8671
Susan R HopkinsPulmonary Imaging Laboratory, UC San Diego Health Sciences, La Jolla, California, United States.ORCID 0000-0002-8672-0986
UC San Diego Health System · US

Funding

Imaging Blood Flow, Ventilation, and Density InteractionsR01HL119201 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2016 to 2019
$2.5M
Imaging Hypoxic Pulmonary Vasoconstriction in the Aging Lung with Proton MRIR01HL129990 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2016 to 2019
$2.4M
Imaging of pulmonary arterial hypertension with proton MRIR56HL159710 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2022 to 2022
$684k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL119201HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL129990HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R56HL159710NHLBI NIH HHS R01 HL119201NHLBI NIH HHS R01 HL129990NHLBI NIH HHS R56 HL159710
6 · The paper itself

Abstract

Ventilation-perfusion matching occurs passively and is also actively regulated through hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly normal subjects, is uncertain. Current evaluation of HPV assesses changes in ventilation-perfusion relationships/pulmonary vascular resistance with hypoxia and is invasive, or unsuitable for patients because of safety concerns. We used a noninvasive imaging-based approach to quantify the pulmonary vascular response to oxygen as a metric of HPV by measuring perfusion changes between breathing 21% and 30%O

Indexed as

HyperoxiaPapillomavirus InfectionsAdultHumansHypoxiaLungMagnetic Resonance ImagingMiddle AgedOxygenProtonsPulmonary CirculationVasoconstrictionYoung AdultOxygenProtonsarterial spin labelinghypoxic pulmonary vasoconstrictionproton MRIquantitative imagingventilation-perfusion matching

Identifiers

PMID38385182
PMCPMC11343071
OpenAlexW4392057742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.