Evidence map›Paper›PMID 38385108›Full record

ArticleOncology letters2024

Rapamycin inhibits B16 melanoma cell viability

Penghui Wang, Haifang Zhang, Kaikai Guo, Chun Liu, Shimin Chen, Baopeng Pu, Sirun Chen, Tong Feng, Hanyi Jiao, Chang Gao

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Autophagy in Melanoma: Molecular Mechanisms and Therapeutic Perspectives.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. mTORC1 regulates the proliferation of SOX9Histochemistry and cell biology · 2025
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Penghui WangDepartment of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Haifang ZhangHainan Institute for Drug Control, Haikou, Hainan 570216, P.R. China.
Kaikai GuoDepartment of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Chun LiuHainan Institute for Drug Control, Haikou, Hainan 570216, P.R. China.
Shimin ChenDepartment of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Baopeng PuDepartment of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Sirun ChenHainan Medical University Press, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Tong FengSchool of Pharmacy, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Hanyi JiaoDepartment of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Chang GaoDepartment of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, Hainan 570100, P.R. China.
Hainan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapamycin is an immunosuppressant that has been shown to prevent tumor growth following organ transplantation. However, its exact mode of antitumor action remains unknown. The present study used the B16-F10 (B16) murine melanoma model to explore the antitumor mechanism of rapamycin, and it was revealed that rapamycin reduced B16 cell viability

Indexed as

apoptosisautophagyB16 melanoma cellscell cyclemTOR/p70-S6k signaling pathwayrapamycin

Identifiers

PMID38385108
PMCPMC10877231
OpenAlexW4391485305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.