ArticleFrontiers in neurology2024
Incidence, clinical features, and outcomes of posterior circulation ischemic stroke: insights from a large multiethnic stroke database.
Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Diagnostic Accuracy of Machine Learning Models in Predicting Functional Outcome of Thrombectomy for Acute Posterior Circulation Artery Occlusion: a Systematic Review and Meta-Analysis.Clinical neuroradiology · 2026Pooled it
- Bridging therapy versus direct endovascular thrombectomy in basilar artery occlusion stroke: a systematic review and meta-analysis.GeroScience · 2026Pooled it
- Endovascular Therapy Versus Best Medical Treatment in Posterior Cerebral Artery Stroke: A Systematic Review and Meta-Analysis.Brain and behavior · 2026Pooled it
- Computed Tomography-Based Imaging Scores in Basilar Artery Occlusions: A Comparison of Predictive Abilities for Functional Outcomes.Stroke (Hoboken, N.J.) · 2026Article
- A hybrid model based on vessel wall magnetic resonance imaging predicts recurrence in posterior circulation ischemic stroke: a multi-institutional study.Journal of neurointerventional surgery · 2026Article
- Unrecognized Atrial Septal Defect Presenting with Postoperative Occipital Infarction.Diagnostics (Basel, Switzerland) · 2026Article
- Toward precision acupuncture: phlegm-dampness pattern as a candidate metabolic-microbial endotype in posterior circulation ischemic vertigo: a narrative review.Frontiers in neurology · 2026Review
- Validity of Nonspecific Stroke Location ICD-10 Subcodes: A Descriptive Study.Cerebrovascular diseases extra · 2026Article
- Deriving a Simple Clinical Predictive Score for Posterior Circulation Ischemic Stroke (PCS-SCORE).Journal of central nervous system disease · 2026Article
- Treatment with Manganese Porphyrin, MnTnBuOE-2-PyPPharmaceuticals (Basel, Switzerland) · 2025Article
- Utilizing machine learning to facilitate the early diagnosis of posterior circulation stroke.BMC neurology · 2024Article
- Assessing the Role of Serum Prealbumin in Prognostic Studies of Stroke: Reflections on Existing Research Methods [Letter].Clinical epidemiology · 2024Article
- Machine learning-based prediction of one-year mortality in ischemic stroke patients.Oxford open neuroscience · 2024Article
- Endovascular recanalization for acute posterior cerebral artery occlusion: a pre-specified secondary analysis of the ATTENTION, BAOCHE, and PLATO studies.Frontiers in neurologyArticle
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Authors and funding
26 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Posterior cerebral circulation ischemic stroke (PCS) comprises up to 25% of all strokes. It is characterized by variable presentation, leading to misdiagnosis and morbidity and mortality. We aim to describe PCS in large multiethnic cohorts. Methods: A retrospective review of a large national stroke database from its inception on the 1st of January 2014 till 31 December 2020. Incidence per 100,000 adult population/year, demographics, clinical features, stroke location, and outcomes were retrieved. We divided the cohort into patients from MENA (Middle East and North Africa) and others. Results: In total, 1,571 patients were identified. The incidence of PCS was observed to be rising and ranged from 6.3 to 13.2/100,000 adult population over the study period. Men were 82.4% of the total. The mean age was 54.9 ± 12.7 years (median 54 years, IQR 46, 63). MENA patients comprised 616 (39.2%) while others were 954 (60.7%); of these, the majority (80.5%) were from South Asia. Vascular risk factors were prevalent with 1,230 (78.3%) having hypertension, 970 (61.7%) with diabetes, and 872 (55.5%) having dyslipidemia. Weakness (944, 58.8%), dizziness (801, 50.5%), and slurred speech (584, 36.2%) were the most commonly presenting symptoms. The mean National Institute of Health Stroke Score (NIHSS) score was 3.8 ± 4.6 (median 3, IQR 1, 5). The overall most frequent stroke location was the distal location (568, 36.2%). The non-MENA cohort was younger, less vascularly burdened, and had more frequent proximal stroke location ( Conclusion: In a multiethnic cohort of posterior circulation stroke patients from the MENA region and South Asia, we noted a rising incidence over time, high prevalence of vascular risk factors, and poor outcomes in older men from the MENA region. We also uncovered considerable disparities between the MENA and non-MENA groups in stroke location and outcome. These disparities are crucial factors to consider when tailoring individualized patient care plans. Further research is needed to thoroughly investigate the underlying reasons for these variations.
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