Evidence map›Paper›PMID 38385014›Full record

ArticleFrontiers in nutrition2024

Urine Se concentration poorly predicts plasma Se concentration at sub-district scales in Zimbabwe, limiting its value as a biomarker of population Se status.

Beaula Mutonhodza, Mavis P Dembedza, Edward J M Joy, Muneta G Manzeke-Kangara, Handrea Njovo, Tasiana K Nyadzayo, R Murray Lark, Alexander A Kalimbira, Elizabeth H Bailey, Martin R Broadley and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Beaula MutonhodzaDepartment of Nutrition, Dietetics and Food Sciences, University of Zimbabwe, Harare, Zimbabwe.
Mavis P DembedzaDepartment of Nutrition, Dietetics and Food Sciences, University of Zimbabwe, Harare, Zimbabwe.
Edward J M JoyLondon School for Hygiene & Tropical Medicine, London, United Kingdom.
Muneta G Manzeke-KangaraRothamsted Research, West Common, Harpenden, United Kingdom.
Handrea NjovoNational Nutrition Unit, Ministry of Health and Child Care of Zimbabwe, Harare, Zimbabwe.
Tasiana K NyadzayoNational Nutrition Unit, Ministry of Health and Child Care of Zimbabwe, Harare, Zimbabwe.
R Murray LarkSchool of Biosciences, University of Nottingham, Loughborough, United Kingdom.
Alexander A KalimbiraDepartment of Human Nutrition and Health, Lilongwe University of Agriculture and Natural Resources, Lilongwe, Malawi.
Elizabeth H BaileySchool of Biosciences, University of Nottingham, Loughborough, United Kingdom.
Martin R BroadleyRothamsted Research, West Common, Harpenden, United Kingdom.
Tonderayi M MatsungoDepartment of Nutrition, Dietetics and Food Sciences, University of Zimbabwe, Harare, Zimbabwe.
Prosper ChoperaDepartment of Nutrition, Dietetics and Food Sciences, University of Zimbabwe, Harare, Zimbabwe.
University of Zimbabwe · ZWRothamsted Research · GBMinistry of Health and Child Welfare · ZWUniversity of Nottingham · GBLilongwe University of Agriculture and Natural Resources · MW

Funding

Gates Foundation INV-009129
6 · The paper itself

Abstract

Introduction: The current study investigated the value of urine selenium (Se) concentration as a biomarker of population Se status in rural sub-Saharan Africa. Method: Urine and plasma Se concentrations were measured among children aged 6-59 months ( Results: The median (Q1, Q3) urine Se concentrations were 8.4 μg/L (5.3, 13.5) and 10.5 μg/L (6.5, 15.2) in children and WRA, respectively. There was moderate evidence for a relationship between urine Se concentration and plasma Se concentration in children ( Discussion: Urine Se concentration poorly predicted plasma Se concentration at sub-district scales in Zimbabwe, limiting its value as a biomarker of population Se status in this context. Further research is warranted at wider spatial scales to determine the value of urine Se as a biomarker when there is greater heterogeneity in Se exposure.

Indexed as

biomarkersdietary selenium intakeestimated average requirementiodothyronine deiodinasemicronutrient surveillanceselenium deficiency

Identifiers

PMID38385014
PMCPMC10879291
OpenAlexW4391609151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.