ArticleFrontiers in veterinary science2024
Multi-omics analysis on the mechanism of the effect of Isatis leaf on the growth performance of fattening sheep.
Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Application of the "Yuyang Muxin" Breeding Chip in Huang-Huai Sheep: A Six-Year Comprehensive Evaluation of Production and Meat Quality Traits.Animals : an open access journal from MDPI · 2026Article
- Purslane supplementation improved antioxidant capacity and milk quality potentially through rumen microbiota in dairy goats.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
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Abstract
Introduction: This study evaluated the effects of Isatis Leaf (ISL) on the growth performance, gastrointestinal tissue morphology, rumen and intestinal microbiota, rumen, serum and urine metabolites, and rumen epithelial tissue transcriptome of fattening sheep. Methods: Twelve 3.5-month-old healthy fattening sheep were randomly divided into two groups, each with 6 replicates, and fed with basal diet (CON) and basal diet supplemented with 80 g/kg ISL for 2.5 months. Gastrointestinal tract was collected for histological analysis, rumen fluid and feces were subjected to metagenomic analysis, rumen fluid, serum, and urine for metabolomics analysis, and rumen epithelial tissue for transcriptomics analysis. Results: The results showed that in the ISL group, the average daily gain and average daily feed intake of fattening sheep were significantly lower than those of the CON group ( Conclusion: In summary, the addition of ISL to the diet had the effect of increasing rumen ammonia nitrogen levels, regulating gastrointestinal microbiota, promoting body fat metabolism, and enhancing immunity in fattening sheep.
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