Evidence map›Paper›PMID 38384855›Full record

ArticleiScience2024

The value of earlier-in-life systolic and diastolic blood pressure for cardiovascular risk prediction.

Andreas Leiherer, Wolfgang Brozek, Axel Muendlein, Hanno Ulmer, Christoph H Saely, Peter Fraunberger, Gabriele Nagel, Emanuel Zitt, Heinz Drexel, Hans Concin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Andreas LeihererVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Wolfgang BrozekAgency for Preventive and Social Medicine, Bregenz, Austria.
Axel MuendleinVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Hanno UlmerAgency for Preventive and Social Medicine, Bregenz, Austria.
Christoph H SaelyVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Peter FraunbergerPrivate University in the Principality of Liechtenstein, Triesen, Liechtenstein.
Gabriele NagelAgency for Preventive and Social Medicine, Bregenz, Austria.
Emanuel ZittAgency for Preventive and Social Medicine, Bregenz, Austria.
Heinz DrexelVorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria.
Hans ConcinAgency for Preventive and Social Medicine, Bregenz, Austria.
Landeskrankenhaus Feldkirch · ATPrivate University in the Principality of Liechtenstein · LIInnsbruck Medical University · ATUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood pressure (BP) varies over a lifetime. This cardiovascular observation study (OS) compared the predictive value of earlier- and later-in-life blood pressure (BP) in 1,497 cardiovascular disease patients utilizing readings taken during a health survey (HS) and 15 years later from the same subjects at the baseline of this OS. Prediction of the cardiovascular risk during the OS follow-up (21 years) was significantly more effective if the earlier BP readings at HS were used instead of recent OS readings (NRI = 0.30, p < 0.001). For HS readings, each 10 mm Hg increase of systolic and diastolic BP was associated with a 17% and 20% higher risk, respectively. At OS, systolic BP lost significance and diastolic BP reversed its association. Noteworthy, different BP categorizations (European vs. US guidelines) yielded similar results. This study highlights the poor predictive power of BP readings in elderly cardiovascular disease patients but emphasizes the significant prognostic value of earlier-in-life BP.

Indexed as

Biological sciencesGeriatricsHealth sciencesPublic health

Identifiers

PMID38384855
PMCPMC10879708
OpenAlexW4391486910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.