Evidence map›Paper›PMID 38384456›Full record

ArticleFrontiers in immunology2024

Redox processes are major regulators of leukotriene synthesis in neutrophils exposed to bacteria

Ekaterina A Golenkina, Galina M Viryasova, Svetlana I Galkina, Natalia D Kondratenko, Tatjana V Gaponova, Yulia M Romanova, Konstantin G Lyamzaev, Boris V Chernyak, Galina F Sud'ina

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ekaterina A GolenkinaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Galina M ViryasovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Svetlana I GalkinaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Natalia D KondratenkoBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Tatjana V GaponovaNational Research Center for Hematology, Russia Federation Ministry of Public Health, Moscow, Russia.
Yulia M RomanovaDepartment of Genetics and Molecular Biology, Gamaleya National Research Centre of Epidemiology and Microbiology, Moscow, Russia.
Konstantin G LyamzaevBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Boris V ChernyakBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Galina F Sud'inaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Lomonosov Moscow State University · RUGamalei Institute of Epidemiology and Microbiology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils play a primary role in protecting our body from pathogens. When confronted with invading bacteria, neutrophils begin to produce leukotriene B4, a potent chemoattractant that, in cooperation with the primary bacterial chemoattractant fMLP, stimulates the formation of swarms of neutrophils surrounding pathogens. Here we describe a complex redox regulation that either stimulates or inhibits fMLP-induced leukotriene synthesis in an experimental model of neutrophils interacting with

Indexed as

Leukotriene B4NeutrophilsAcetylcysteineAntioxidantsChemotactic FactorsDiamideGlutathioneLeukotrienesOxidation-ReductionSalmonella typhimuriumSulfhydryl CompoundsAcetylcysteineAntioxidantsChemotactic FactorsDiamideGlutathioneLeukotriene B4LeukotrienesSulfhydryl Compoundsglutathioneleukotriene B4neutrophilneutrophil swarmingreactive oxygen speciesSalmonella typhimurium

Identifiers

PMID38384456
PMCPMC10880102
OpenAlexW4391604604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.